Pulmonary metastasectomy in colorectal cancer: the PulMiCC trial

被引:88
作者
Treasure, Tom [1 ]
Fallowfield, Lesley [2 ]
Lees, Belinda [3 ]
Farewell, Vern [4 ]
机构
[1] UCL, Dept Math, Clin Operat Res Unit, London WC1H 0BT, England
[2] Univ Sussex, Brighton & Sussex Med Sch, Brighton, E Sussex, England
[3] Royal Brompton Hosp, Clin Trials & Evaluat Unit, London SW3 6LY, England
[4] Univ Forvie Site, MRC Biostat Unit, Inst Publ Hlth, Cambridge, England
关键词
RANDOMIZED CLINICAL-TRIALS; THORACIC SURGEONS; EUROPEAN-SOCIETY; MINIMIZATION; RESECTION; THERAPY;
D O I
10.1136/thoraxjnl-2011-200015
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
PulMiCC (Pulmonary Metastasectomy in Colorectal Cancer) is a randomised controlled trial funded by Cancer Research UK. Patients with a history of resected colorectal cancer who are found to have pulmonary metastases are first registered for evaluation and, if subsequently eligible for the trial, they are invited to be randomly allocated to 'active monitoring' or 'active monitoring with pulmonary metastasectomy'. The clinical outcomes are overall survival, relapse-free survival, lung function and patient-reported quality of life.
引用
收藏
页码:185 / 187
页数:3
相关论文
共 19 条
[1]   THE EFFECT OF METASTASECTOMY - FACT OR FICTION [J].
ABERG, T ;
MALMBERG, KA ;
NILSSON, B ;
NOU, E .
ANNALS OF THORACIC SURGERY, 1980, 30 (04) :378-384
[2]   Treatment allocation by minimisation [J].
Altman, DG ;
Bland, JM .
BRITISH MEDICAL JOURNAL, 2005, 330 (7495) :843-843
[3]   Imaging Requirements in the Practice of Pulmonary Metastasectomy [J].
Detterbeck, Frank C. ;
Grodzki, Tomasz ;
Gleeson, Fergus ;
Robert, John H. .
JOURNAL OF THORACIC ONCOLOGY, 2010, 5 (06) :S134-S139
[4]   Pulmonary metastasectomy in colorectal cancer: a systematic review and quantitative synthesis [J].
Fiorentino, Francesca ;
Hunt, Ian ;
Teoh, Kristine ;
Treasure, Tom ;
Utley, Martin .
JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, 2010, 103 (02) :60-66
[5]   Pulmonary Metastasectomy A Survey of Current Practice Amongst Members of the European Society of Thoracic Surgeons [J].
Internullo, Eveline ;
Cassivi, Stephen D. ;
Van Raemdonck, Dirk ;
Friedel, Godehard ;
Treasure, Tom ;
Berrisford, Richard ;
Detterbeck, Frank ;
Furrer, Markus ;
Yuste, Mariano Garcia ;
Gebitekin, Cengiz ;
Grodzki, Tomasz ;
Hensens, Ab ;
Jakovic, Radislav ;
Klepetko, Walter ;
Migliore, Marcello ;
Molnar, Thomas ;
Paleru, Christian ;
Robert, John ;
Rocco, Gaetano ;
Rolle, Axel ;
Turna, Akif ;
Van Schil, Paul ;
Vaughan, Roger ;
Venuta, Federico .
JOURNAL OF THORACIC ONCOLOGY, 2008, 3 (11) :1257-1266
[6]   Information needs of patients with cancer: results from a large study in UK cancer centres [J].
Jenkins, V ;
Fallowfield, L ;
Saul, J .
BRITISH JOURNAL OF CANCER, 2001, 84 (01) :48-51
[7]   Discussing randomised clinical trials of cancer therapy: evaluation of a Cancer Research LTK training programme [J].
Jenkins, V ;
Fallowfield, L ;
Solis-Trapala, I ;
Langridge, C ;
Farewell, V .
BMJ-BRITISH MEDICAL JOURNAL, 2005, 330 (7488) :400-403
[8]   Reasons for accepting or declining to participate in randomized clinical trials for cancer therapy [J].
Jenkins, V ;
Fallowfield, L .
BRITISH JOURNAL OF CANCER, 2000, 82 (11) :1783-1788
[9]   What Are the Considerations in the Surgical Approach in Pulmonary Metastasectomy? [J].
Molnar, Tamas F. ;
Gebitekin, Cengiz ;
Turna, Akif .
JOURNAL OF THORACIC ONCOLOGY, 2010, 5 (06) :S140-S144
[10]  
Myrdal G, 2004, THORAX, V59, P45