Optical fiber-based sensors: application to chemical biology

被引:54
作者
Brogan, KL [1 ]
Walt, DR [1 ]
机构
[1] Tufts Univ, Dept Chem, Medford, MA 02155 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/j.cbpa.2005.08.009
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Optical fibers have been used to develop sensors based on nucleic acids and cells. Sensors employing DNA probes have been developed for various genomics applications and microbial pathogen detection. Live cell-based sensors have enabled the monitoring of environmental toxins, and have been used for fundamental studies on populations of individual cells. Both single-core optical fiber sensors and optical fiber sensor arrays have been used for sensing based on nucleic acids and live cells.
引用
收藏
页码:494 / 500
页数:7
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