Mre11-Rad50 complex crystals suggest molecular calisthenics

被引：12

作者：

Wyman, Claire ^{[1
]}

Lebbink, Joyce ^{[1
]}

Kanaar, Roland ^{[1
]}

机构：

[1] Erasmus Univ, Med Ctr, Dept Radiat Oncol, Dept Genet & Canc, NL-3000 CA Rotterdam, Netherlands

来源：

DNA REPAIR | 2011年 / 10卷 / 10期

关键词：

Genome maintenance; DNA double-strand breaks; DNA repair; STRAND-BREAK REPAIR; DNA-REPAIR; STRUCTURAL BIOCHEMISTRY; NUCLEASE ACTIVITIES; HUMAN RAD50/MRE11; MISMATCH REPAIR; MRE11; NUCLEASE; PROTEIN MUTS; MRN COMPLEX; RAD50;

D O I：

10.1016/j.dnarep.2011.07.008

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Recently published crystal structures of different Mre11 and Rad50 complexes show the arrangement of these proteins and imply dramatic ligand-induced rearrangements with important functional consequences. (C) 2011 Elsevier B.V. All rights reserved.

引用

页码：1066 / 1070

页数：5

共 33 条

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