Broad spectrum antiviral nucleosides-Our best hope for the future

被引:14
作者
Seley-Radtke, Katherine L. [1 ]
Thames, Joy E. [1 ]
Waters, Charles D., III [1 ]
机构
[1] Univ Maryland Baltimore Cty, Dept Chem & Biochem, Baltimore, MD 21228 USA
来源
CORONAVIRUSES AND OTHER NOVEL ANTIVIRAL TARGETS | 2021年 / 57卷
关键词
HUMAN-IMMUNODEFICIENCY-VIRUS; POSITIVE CHRONIC HEPATITIS; B-E-ANTIGEN; ADEFOVIR DIPIVOXIL; REVERSE-TRANSCRIPTASE; DNA POLYMERASE; C VIRUS; INHIBITION; RIBAVIRIN; CIDOFOVIR;
D O I
10.1016/bs.armc.2021.09.001
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
引用
收藏
页码:109 / 132
页数:24
相关论文
共 123 条
[91]   Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial [J].
Sculier, Delphine ;
Wandeler, Gilles ;
Yerly, Sabine ;
Marinosci, Annalisa ;
Stoeckle, Marcel ;
Bernasconi, Enos ;
Braun, Dominique L. ;
Vernazza, Pietro ;
Cavassini, Matthias ;
Buzzi, Marta ;
Metzner, Karin J. ;
Decosterd, Laurent A. ;
Gunthard, Huldrych F. ;
Schmid, Patrick ;
Limacher, Andreas ;
Egger, Matthias ;
Calmy, Alexandra .
PLOS MEDICINE, 2020, 17 (11)
[92]  
Seley-Radtke K, 2018, ANTIVIR CHEM CHEMOTH, V26
[93]   The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold [J].
Seley-Radtke, Katherine L. ;
Yates, Mary K. .
ANTIVIRAL RESEARCH, 2018, 154 :66-86
[94]  
Shaw M. M., 2001, Antiviral Chemistry and Chemotherapy, V12, P175
[95]   An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice [J].
Sheahan, Timothy P. ;
Sims, Amy C. ;
Zhou, Shuntai ;
Graham, Rachel L. ;
Pruijssers, Andrea J. ;
Agostini, Maria L. ;
Leist, Sarah R. ;
Schafer, Alexandra ;
Dinnon, Kenneth H., III ;
Stevens, Laura J. ;
Chappell, James D. ;
Lu, Xiaotao ;
Hughes, Tia M. ;
George, Amelia S. ;
Hill, Collin S. ;
Montgomery, Stephanie A. ;
Brown, Ariane J. ;
Bluemling, Gregory R. ;
Natchus, Michael G. ;
Saindane, Manohar ;
Kolykhalov, Alexander A. ;
Painter, George ;
Harcourt, Jennifer ;
Tamin, Azaibi ;
Thornburg, Natalie J. ;
Swanstrom, Ronald ;
Denison, Mark R. ;
Baric, Ralph S. .
SCIENCE TRANSLATIONAL MEDICINE, 2020, 12 (541)
[96]   Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses [J].
Sheahan, Timothy P. ;
Sims, Amy C. ;
Graham, Rachel L. ;
Menachery, Vineet D. ;
Gralinski, Lisa E. ;
Case, James B. ;
Leist, Sarah R. ;
Pyrc, Krzysztof ;
Feng, Joy Y. ;
Trantcheva, Iva ;
Bannister, Roy ;
Park, Yeojin ;
Babusis, Darius ;
Clarke, Michael O. ;
Mackman, Richard L. ;
Spahn, Jamie E. ;
Palmiotti, Christopher A. ;
Siegel, Dustin ;
Ray, Adrian S. ;
Cihlar, Tomas ;
Jordan, Robert ;
Denison, Mark R. ;
Baric, Ralph S. .
SCIENCE TRANSLATIONAL MEDICINE, 2017, 9 (396)
[97]   A comparative analysis of remdesivir and other repurposed antivirals against SARS-CoV-2 [J].
Simonis, Alexander ;
Theobald, Sebastian J. ;
Fatkenheuer, Gerd ;
Rybniker, Jan ;
Malin, Jakob J. .
EMBO MOLECULAR MEDICINE, 2021, 13 (01)
[98]   Entecavir: A new nucleoside analog for the treatment of chronic hepatitis B infection [J].
Sims, Keri A. ;
Woodland, Abigail M. .
PHARMACOTHERAPY, 2006, 26 (12) :1745-1757
[99]   Sofosbuvir use for yellow fever: a new perspective treatment [J].
Siqueira-Batista, Rodrigo ;
Bayao, Taciana De Souza ;
Cupertino, Marli Do Carmo ;
Joseph Mayers, Nicholas Alfred ;
Gomes, Andreia Patricia .
PATHOGENS AND GLOBAL HEALTH, 2019, 113 (05) :207-208
[100]  
Smee Donald F., 2006, Antiviral Chemistry & Chemotherapy, V17, P185