Broad spectrum antiviral nucleosides-Our best hope for the future

被引:14
作者
Seley-Radtke, Katherine L. [1 ]
Thames, Joy E. [1 ]
Waters, Charles D., III [1 ]
机构
[1] Univ Maryland Baltimore Cty, Dept Chem & Biochem, Baltimore, MD 21228 USA
来源
CORONAVIRUSES AND OTHER NOVEL ANTIVIRAL TARGETS | 2021年 / 57卷
关键词
HUMAN-IMMUNODEFICIENCY-VIRUS; POSITIVE CHRONIC HEPATITIS; B-E-ANTIGEN; ADEFOVIR DIPIVOXIL; REVERSE-TRANSCRIPTASE; DNA POLYMERASE; C VIRUS; INHIBITION; RIBAVIRIN; CIDOFOVIR;
D O I
10.1016/bs.armc.2021.09.001
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
引用
收藏
页码:109 / 132
页数:24
相关论文
共 123 条
[1]   Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease [J].
Agostini, Maria L. ;
Andres, Erica L. ;
Sims, Amy C. ;
Graham, Rachel L. ;
Sheahan, Timothy P. ;
Lu, Xiaotao ;
Smith, Everett Clinton ;
Case, James Brett ;
Feng, Joy Y. ;
Jordan, Robert ;
Ray, Adrian S. ;
Cihlar, Tomas ;
Siegel, Dustin ;
Mackman, Richard L. ;
Clarke, Michael O. ;
Baric, Ralph S. ;
Denison, Mark R. .
MBIO, 2018, 9 (02)
[2]   Current knowledge about the antivirals remdesivir (GS-5734) and GS-441524 as therapeutic options for coronaviruses [J].
Amirian, E. Susan ;
Levy, Julie K. .
ONE HEALTH, 2020, 9
[3]  
Beasley D., 2021, REUTERS
[4]   Safety, Pharmacokinetics, and Antiviral Activity of AT-527, a Novel Purine Nucleotide Prodrug, in Hepatitis C Virus-Infected Subjects with or without Cirrhosis [J].
Berliba, Elina ;
Bogus, Maxim ;
Vanhoutte, Frederic ;
Berghmans, Pieter-Jan ;
Good, Steven S. ;
Moussa, Adel ;
Pietropaolo, Keith ;
Murphy, Robert L. ;
Zhou, Xiao-Jian ;
Sommadossi, Jean-Pierre .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2019, 63 (12)
[5]   Orally available cidofovir derivative active against smallpox [J].
Bradbury, J .
LANCET, 2002, 359 (9311) :1041-1041
[6]   Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication [J].
Bravo, Jack P. K. ;
Dangerfield, Tyler L. ;
Taylor, David W. ;
Johnson, Kenneth A. .
MOLECULAR CELL, 2021, 81 (07) :1548-+
[7]  
Cahard D, 2004, MINI-REV MED CHEM, V4, P371
[8]   Treatment of hepatitis B e antigen - Positive chronic hepatitis with telbivudine or adefovir [J].
Chan, Henry L. Y. ;
Heathcote, E. Jenny ;
Marcellin, Patrick ;
Lai, Ching-Lung ;
Cho, Mong ;
Moon, Young M. ;
Chao, You-Chen ;
Myers, Robert P. ;
Minuk, Gerald Y. ;
Jeffers, Lennox ;
Sievert, William ;
Bzowej, Natalie ;
Harb, George ;
Kaiser, Ralf ;
Qiao, Xin-Jian ;
Brown, Nathaniel A. .
ANNALS OF INTERNAL MEDICINE, 2007, 147 (11) :745-U14
[9]   An expert review on the use of tenofovir alafenamide for the treatment of chronic hepatitis B virus infection in Asia [J].
Charlton, Michael R. ;
Alam, Altaf ;
Shukla, Akash ;
Dashtseren, Bekhbold ;
Lesmana, Cosmas Rinaldi Adithya ;
Duger, Davadoorj ;
Payawal, Diana Alcantara ;
Duy Cuong, Do ;
Jargalsaikhan, Ganbolor ;
Cua, Ian Homer Yee ;
Sollano, Jose Decena ;
Singh, Karam Romeo ;
Madan, Kaushal ;
Win, Khin Maung ;
Kyi, Khin Pyone ;
Tun, Kyaw Soe ;
Salih, Mohd. ;
Rastogi, Mukul ;
Saraf, Neeraj ;
Thuy, Pham Thi Thu ;
Hien, Pham Tran Dieu ;
Gani, Rino Alvani ;
Mohamed, Rosmawati ;
Tanwandee, Tawesak ;
Piratvisuth, Teerha ;
Sukeepaisarnjaroen, Wattana ;
Naing, Win ;
Hashmi, Zahid Yasin .
JOURNAL OF GASTROENTEROLOGY, 2020, 55 (09) :811-823
[10]   Development of cytarabine prodrugs and delivery systems for leukemia treatment [J].
Chhikara, Bhupender S. ;
Parang, Keykavous .
EXPERT OPINION ON DRUG DELIVERY, 2010, 7 (12) :1399-1414