Synthesis of Substituted 1,4,5,6-Tetrahydrocyclopenta[b]pyrroles by Platinum-Catalyzed Cascade Cyclization/Ring Expansion of 2-Alkynyl-1-azaspiro[2.3]hexanes

被引：32
|
作者：
Yoshida, Masahiro [1 ]
Maeyama, Yohei [1 ]
Al-Amin, Mohammad [1 ]
Shishido, Kozo [1 ]
机构：
[1] Univ Tokushima, Grad Sch Pharmaceut Sci, Tokushima 7708505, Japan
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 76卷 / 14期
基金：
日本学术振兴会;
关键词：
EFFICIENT SYNTHESIS; PYRROLES; GOLD; ACTIVATION; OXIDATION; ALKENES; TOOL;
D O I：
10.1021/jo201000f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reaction of 2-allcynyl-1-azaspiro[2.3]hexanes with a platinum catalyst is described. 1,4,5,6-Tetrahydrocyclopenta[b]pyrroles having a variety of substituents were conveniently synthesized via a cascade cyclization/ring-expansion process.
引用
收藏
页码：5813 / 5820
页数：8
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