Usefulness of the monocyte-to-high-density lipoprotein cholesterol ratio to predict bare metal stent restenosis

被引：45
作者：
Yilmaz, Samet [1 ]
Akboga, Mehmet K. [2 ]
Sen, Fatih [2 ]
Balci, Kevser G. [2 ]
Aras, Dursun [2 ]
Temizhan, Ahmet [2 ]
Aydogdu, Sinan [2 ]
机构：
[1] Yozgat State Hosp, Cardiovasc Dept, TR-66200 Yozgat, Turkey
[2] Turkey Yuksek Ihtisas Educ & Res Hosp, Cardiol Clin, TR-06100 Ankara, Turkey
来源：
BIOMARKERS IN MEDICINE | 2016年 / 10卷 / 09期
关键词：
high-density lipoprotein cholesterol; inflammation; monocyte count; stent restenosis; PERCUTANEOUS CORONARY INTERVENTION; ASSOCIATION TASK-FORCE; LYMPHOCYTE RATIO; INFLAMMATORY BIOMARKERS; ANGIOGRAPHIC RESTENOSIS; PRACTICE GUIDELINES; ANGIOPLASTY;
D O I：
10.2217/bmm-2016-0069
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Aim: The aim of the present study was to investigate the predictive value of preprocedural monocyte count-to-high-density lipoprotein cholesterol ratio (MHR) on development of in-stent restenosis in patients undergoing coronary bare-metal stent (BMS) implantation. Patients & methods: Data from 705 patients who had undergone BMS implantation and additional control coronary angiography were analyzed. Results: Patients were divided into three tertiles based on preprocedural MHR. Restenosis occurred in 59 patients (25%) in the lowest tertile, 84 (35%) in the middle tertile and 117 (50%) in the highest MHR tertile (p < 0.001). Using multiple logistic regression analysis, smoking, diabetes mellitus, stent length, preprocedural MHR and C-reactive protein levels emerged as independent predictors of in-stent restenosis. Conclusion: High preprocedural MHR is related to BMS restenosis.
引用
收藏
页码：959 / 966
页数：8
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