Restless legs syndrome and sleep problems in children and adolescents with insulin-dependent diabetes mellitus type 1

被引:29
作者
Happe, S
Treptau, N
Ziegler, R
Harms, E
机构
[1] Univ Gottingen, Dept Clin Neurophysiol, D-37099 Gottingen, Germany
[2] Univ Munster, Dept Paediat, Ctr Diabet, D-4400 Munster, Germany
[3] Elisabeth Hosp, Dept Child & Youth Med, Essen, Germany
[4] Paediat Diabet Ctr, Munster, Germany
关键词
restless legs syndrome; children; adolescents; diabetes mellitus type 1; sleep;
D O I
10.1055/s-2005-837685
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The restless legs syndrome (RLS) occurs in adulthood with a prevalence of 5 to 10% and can be associated with diabetes mellitus. The prevalence in childhood, however, is unknown. We asked consecutive children with type 1 (insulin-dependent) diabetes mellitus as well as their parents and siblings about RLS according to a standardised questionnaire. Altogether, 46 patients (25 female, 12.0 +/- 3.7 years), 50 siblings (29 female, 12.3 +/- 5.5 years) and 75 parents (41 mothers, 40.4 +/- 5.1 years; 34 fathers, 42.5 +/- 5.3 years; 1.3% with diabetes mellitus) were included. One patient (2.2%), one sibling (2.0%), and 14 parents (18.7%) were diagnosed as having RLS. Disturbances of sleep initiating, sleep maintenance and daytime tiredness were similar in patients and siblings. There was a significant association of higher HbA1c values (mean 7.7 +/- 2.2 %) with sleep initiating problems. The mean dose of international units of insulin/kg body weight/ day (0.79 +/- 0.26 IU) was not associated with the presence of RLS or sleep problems. To conclude, there seems to be no association of diabetes mellitus type 1 with RLS in children and adolescents. However, there is a relationship between diabetes and sleep disturbances and an optimally controlled diabetes mellitus might be an important factor for an improved sleep initiation.
引用
收藏
页码:98 / 103
页数:6
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