Modified reactive SMB for production of high concentrated fructose syrup by isomerization of glucose to fructose

被引:27
|
作者
Zhang, Yan
Hidajat, Kus
Ray, Ajay K.
机构
[1] Univ Western Ontario, Dept Chem & Biochem Engn, London, ON N6A 5B9, Canada
[2] Natl Univ Singapore, Dept Chem & Biomol Engn, Singapore 119260, Singapore
关键词
fructose; moving bed bioreactor; bioprocess design; optimization; Varicol; Pareto;
D O I
10.1016/j.bej.2007.01.026
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
This work presents modifications to the Hashimoto's hybrid simulated moving bed reactor (SMBR) system which was used to produce 55% high fructose syrup (HFS55). The purpose of this study is to develop a new SMBR system to overcome the disadvantages of Hashimoto system (3-zone SMB with seven reactors), i.e., low utility of reactors when feed being a 50/50 blend of glucose and fructose. Two different configurations of modified system were presented in this paper: the first configuration is 4-zone SMB with one reactor, while the other one consists of one additional reactor. Both of these configurations aim at improving the concentration and purity of glucose at the inlet of the reactor, which will lead to both high productivity and high purity of fructose in the product. A state-of-the-art optimization technique, viz., non-dominated sorting genetic algorithm (NSGA) is used in finding the optimal design and operating parameters for the modified reactive SMB and Varicol processes. Compared with the Hashimoto's system, high productivity and purity of fructose can be achieved in these new systems using less number of reactors. (C) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:341 / 351
页数:11
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