Synthetic approaches to the 2004 new drugs

被引：26

作者：

Li, J ^{[1
]}

Liu, KKC ^{[1
]}

Sakya, S ^{[1
]}

机构：

[1] Pfizer Inc, Pfizer Global Res & Dev, Groton, CT 06340 USA

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2005年 / 5卷 / 12期

关键词：

synthesis; new drug; new chemical entities;

D O I：

10.2174/138955705774933329

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as leads for designing future drugs. To this end, this review covers the syntheses of 12 NCEs marketed in 2004.

引用

页码：1133 / 1144

页数：12

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