Hypercalcemia due to all trans retinoic acid in the treatment of acute promyelocytic leukemia potentiated by voriconazole

被引：21
作者：
Bennett, MT
Sirrs, S
Yeung, JK
Smith, CA
机构：
[1] Univ British Columbia, Dept Med, Vancouver, BC, Canada
[2] Univ British Columbia, Div Endocrinol, Vancouver, BC, Canada
[3] Univ British Columbia, Fac Pharmaceut Sci, Vancouver, BC, Canada
[4] Univ British Columbia, Div Hematol, Vancouver, BC, Canada
来源：
LEUKEMIA & LYMPHOMA | 2005年 / 46卷 / 12期
关键词：
hypercalcemia; ATRA; all-trans-retinoic acid; APL; acute promyelocytic leukemia; voriconazole;
D O I：
10.1080/10428190500235298
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
All-trans-retinoic acid ( ATRA) is a new and effective treatment of acute promyelocytic leukemia. It has many side-effects, including the retinoic acid syndrome and Sweet's syndrome. There have been only nine cases of hypercalcemia associated with ATRA described in the literature. We discuss a case of hypercalcemia, which we believe was due to inhibition of cytochrome P450 function by voriconizole when used concomitantly with ATRA.
引用
收藏
页码：1829 / 1831
页数：3
相关论文
共 50 条
  • [21] Pharmacology of all-trans-retinoic acid in children with acute promyelocytic leukemia
    Lanvers, C
    Reinhardt, D
    Dübbers, A
    Wagner-Bohn, A
    Creutzig, U
    Ritter, J
    Boos, J
    MEDICAL AND PEDIATRIC ONCOLOGY, 2003, 40 (05): : 293 - 301
  • [22] DIFFERENTIATION OF EXTRAMEDULLARY ACUTE PROMYELOCYTIC LEUKEMIA BY ALL-TRANS-RETINOIC ACID
    LEDERMAN, CA
    WEISBERGER, J
    SEITER, K
    FELDMAN, EJ
    LEUKEMIA & LYMPHOMA, 1995, 18 (1-2) : 189 - 193
  • [23] Thrombosis in patients with acute promyelocytic leukemia treated with and without All-trans retinoic acid
    Escudier, SM
    Kantarjian, HM
    Estey, EH
    LEUKEMIA & LYMPHOMA, 1996, 20 (5-6) : 435 - 439
  • [24] Treatment with all-trans retinoic acid in acute promyelocytic leukemia reduces early deaths in children
    Mann, G
    Reinhardt, D
    Ritter, J
    Hermann, J
    Schmitt, K
    Gadner, H
    Creutzig, U
    ANNALS OF HEMATOLOGY, 2001, 80 (07) : 417 - 422
  • [25] Scrotal ulcers arising during treatment with all-trans retinoic acid for acute promyelocytic leukemia
    Shimizu, D
    Nomura, K
    Matsuyama, R
    Matsumoto, Y
    Ueda, K
    Masuda, K
    Taki, T
    Nishida, K
    Horiike, S
    Kishimoto, S
    Yanagisawa, A
    Taniwaki, M
    INTERNAL MEDICINE, 2005, 44 (05) : 480 - 483
  • [26] Genital ulcers after treatment with all-trans-retinoic acid in a child with acute promyelocytic leukemia
    Ünal, S
    Gümrük, F
    Çetin, M
    Hiçsönmez, G
    PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2005, 22 (05) : 357 - 359
  • [27] Acquired resistance to all-trans retinoic acid therapy in acute promyelocytic leukemia
    Cornic, M
    Delva, L
    Castaigne, S
    Lefebvre, P
    Balitrand, N
    Degos, L
    Chomienne, C
    ONKOLOGIE, 1996, 19 : 10 - 13
  • [28] Pharmacokinetics of all-trans-retinoic acid in Japanese patients with acute promyelocytic leukemia
    Usuki, K
    Endo, M
    Osawa, M
    Kitazume, K
    Iki, S
    Urabe, A
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 1996, 63 (01) : 19 - 23
  • [29] RAPID IMPROVEMENT OF COAGULOPATHY BY ALL-TRANS-RETINOIC ACID IN ACUTE PROMYELOCYTIC LEUKEMIA
    KAWAI, Y
    WATANABE, K
    KIZAKI, M
    MURATA, M
    KAMATA, T
    UCHIDA, H
    MORIKI, T
    YOKOYAMA, K
    TOKUHIRA, M
    NAKAJIMA, H
    HANDA, M
    IKEDA, Y
    AMERICAN JOURNAL OF HEMATOLOGY, 1994, 46 (03) : 184 - 188
  • [30] CHROMOSOME OBSERVATIONS OF ACUTE PROMYELOCYTIC LEUKEMIA TREATED WITH ALL-TRANS RETINOIC ACID
    WU, XZ
    WANG, WW
    ZHOU, ZL
    ZHU, GC
    YANG, ZC
    YING, JS
    ZHU, Y
    HEMATOLOGIC PATHOLOGY, 1992, 6 (01) : 25 - 29
12345