Cell Culture on a Carbon Nanotube Scaffold

被引：45

作者：

Aoki, Naofurni ^{[1
]}

Yokoyama, Atsuro ^{[1
]}

Nodasaka, Yoshinobu

Akasaka, Tsukasa

Uo, Motohiro

Sato, Yoshinori ^{[2
]}

Tohji, Kazuyuki ^{[2
]}

Watari, Furnio

机构：

[1] Hokkaido Univ, Grad Sch Dent Med, Dept Oral Funct Sci, Sapporo, Hokkaido, Japan

[2] Tohoku Univ, Grad Sch Environm Studies, Sendai, Miyagi 980, Japan

来源：

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY | 2005年 / 1卷 / 04期

关键词：

Carbon Nanotubes; Scaffolds; Cell Culture; Osteoblast Cells; Cell Adhesion;

D O I：

10.1166/jbn.2005.048

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

The developments of nanoscale substance such as carbon nanotubes (CNTs) for medical applications have attracted a great deal of attention. In the present study, an attempt was made to development of CNTs as scaffolds for cell culture. CNT scaffolds were formed on polycarbonate membranes by vacuum filtration and cell proliferation and morphology were investigated using a scanning electron microscopy. Osteoblast cells (bone-forming cell) on CNTs showed excellent proliferation with extension of cell morphology in all directions. Numerous filopodia were extended from cells toward the inside of fibrous aggregates of CNTs and tightly bound to scaffolds. These results suggest that CNTs can be used as scaffolds with excellent affinity for cell adhesion.

引用

页码：402 / 405

页数：4

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