Chaperoning the nuclear envelope

被引：0

作者：

Kirstein, Janine ^{[1
]}

机构：

[1] Univ Bremen, Dept Cell Biol, Bremen, Germany

来源：

NATURE CELL BIOLOGY | 2022年 / 24卷 / 11期

关键词：

D O I：

10.1038/s41556-022-01013-8

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

FG-nucleoporins of the nuclear pore complexes form a permeability barrier between the nucleus and the cytosol. FG-nucleoporins contain disordered regions and are prone to aggregation. Two studies identify the chaperone DNAJB6 as a key factor that prevents aggregation of FG-nucleoporins and assists in the biogenesis of nuclear pore complexes.

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页码：1563 / 1564

页数：2

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