Pain relief induced by repetitive transcranial magnetic stimulation of precentral cortex

被引：242
作者：
Lefaucheur, JP
Drouot, X
Keravel, Y
Nguyen, JP
机构：
[1] Hop Henri Mondor, Serv Physiol Explorat Fonct, Hop Paris, F-94010 Creteil, France
[2] Hop Henri Mondor, Serv Neurochirurg, Hop Paris, F-94010 Creteil, France
[3] Fac Med Creteil, INSERM, U421, F-94010 Creteil, France
来源：
NEUROREPORT | 2001年 / 12卷 / 13期
关键词：
clinical neurophysiology; motor cortex stimulation; neurogenic pain; repetitive transcranial magnetic stimulation;
D O I：
10.1097/00001756-200109170-00041
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Chronic electrical stimulation of the precentral (motor) cortex using surgically implanted electrodes is performed to treat medication-resistant neurogenic pain. The goal of this placebo-controlled study was to obtain such antalgic effects by means of a non-invasive cortical stimulation using repetitive transcranial magnetic stimulation (rTMS). Eighteen patients with intractable neurogenic pain of various origins were included and underwent a 20 min session of either 10 Hz, 0.5 Hz or* sham rTMS over the motor cortex in a random order. A significant decrease in the mean pain level of the series was obtained only after 10 Hz rTMS. This study shows that a transient pain relief can be induced by 10 Hz rTMS of the motor cortex in some patients suffering from chronic neurogenic pain. NeuroReport 12:2963-2965 (C) 2001 Lippincott Williams & Wilkins.
引用
收藏
页码：2963 / 2965
页数：3
相关论文
共 20 条
[1]   Electrical stimulation of motor cortex for pain control:: a combined PET-scan and electrophysiological study [J].
García-Larrea, L ;
Peyron, R ;
Mertens, P ;
Gregoire, MC ;
Lavenne, F ;
Le Bars, D ;
Convers, P ;
Mauguière, F ;
Sindou, M ;
Laurent, B .
PAIN, 1999, 83 (02) :259-273
[2]   Mood improvement following daily left prefrontal repetitive transcranial magnetic stimulation in patients with depression: A placebo-controlled crossover trial [J].
George, MS ;
Wassermann, EM ;
Kimbrell, TA ;
Little, JT ;
Williams, WE ;
Danielson, AL ;
Greenberg, BD ;
Hallett, M ;
Post, RM .
AMERICAN JOURNAL OF PSYCHIATRY, 1997, 154 (12) :1752-1756
[3]   A controlled trial of daily left prefrontal cortex TMS for treating depression [J].
George, MS ;
Nahas, Z ;
Molloy, M ;
Speer, AM ;
Oliver, NC ;
Li, XB ;
Arana, GW ;
Risch, SC ;
Ballenger, JC .
BIOLOGICAL PSYCHIATRY, 2000, 48 (10) :962-970
[4]  
Greenberg BD, 1997, AM J PSYCHIAT, V154, P867
[5]   Transcranial magnetic stimulation and auditory hallucinations in schizophrenia [J].
Hoffman, RE ;
Boutros, NN ;
Hu, S ;
Berman, RM ;
Krystal, JH ;
Charney, DS .
LANCET, 2000, 355 (9209) :1073-1075
[6]   Poststroke pain control by chronic motor cortex stimulation: neurological characteristics predicting a favorable response [J].
Katayama, Y ;
Fukaya, C ;
Yamamoto, T .
JOURNAL OF NEUROSURGERY, 1998, 89 (04) :585-591
[7]   Transcranial magnetic stimulation (TMS) in controlled treatment studies: Are some "sham" forms active? [J].
Loo, CK ;
Taylor, JL ;
Gandevia, SC ;
McDarmont, BN ;
Mitchell, PB ;
Sachdev, PS .
BIOLOGICAL PSYCHIATRY, 2000, 47 (04) :325-331
[8]   Precentral cortex stimulation for the treatment of central neuropathic pain - Results of a prospective study in a 20-patient series [J].
Mertens, P ;
Nuti, C ;
Sindou, M ;
Guenot, M ;
Peyron, R ;
Garcia-Larrea, L ;
Laurent, B .
STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 1999, 73 (1-4) :122-125
[9]  
MEYERSON BA, 1993, ACTA NEUROCHIR, P150
[10]   TRANSCRANIAL MAGNETIC COIL STIMULATION OF MOTOR CORTEX IN PATIENTS WITH CENTRAL PAIN [J].
MIGITA, K ;
UOZUMI, T ;
ARITA, K ;
MONDEN, S .
NEUROSURGERY, 1995, 36 (05) :1037-1039
12