GATA2 monoallelic expression underlies reduced penetrance in inherited GATA2-mutated MDS/AML

被引：52

作者：

Al Seraihi, Ahad F. ^{[1
]}

Rio-Machin, Ana ^{[1
]}

Tawana, Kiran ^{[1
]}

Bodor, Csaba ^{[2
]}

Wang, Jun ^{[3
]}

Nagano, Ai ^{[3
]}

Heward, James A. ^{[1
]}

Iqbal, Sameena ^{[1
]}

Beset, Steven ^{[4
]}

Lea, Nicholas ^{[4
]}

McLornan, Donal ^{[5
]}

Kozyra, Emilia J. ^{[6
,7
]}

Wlodarski, Marcin W. ^{[7
]}

Niemeyer, Charlotte M. ^{[7
]}

Scott, Hamish ^{[8
]}

Hahn, Chris ^{[8
]}

Ellison, Alicia ^{[9
]}

Tummala, Hemanth ^{[9
]}

Cardoso, Shirleny Romualdo ^{[9
]}

Vulliamy, Tom ^{[9
]}

Dokal, Inderjeet ^{[9
]}

Butler, Tom ^{[10
]}

Smith, Matthew ^{[10
]}

Cavenagh, Jamie ^{[10
]}

Fitzgibbon, Jude ^{[1
]}

机构：

[1] Queen Mary Univ London, Ctr Haematooncol, Barts Canc Inst, London, England

[2] Semmelweis Univ, MTA SE Lendulet Mol Oncohematol Res Grp, Dept Pathol & Expt Canc Res 1, Budapest, Hungary

[3] Queen Mary Univ London, Ctr Mol Oncol, Barts Canc Inst, London, England

[4] Kings Coll Hosp NHS Fdn Trust, Lab Mol Haematooncol, London, England

[5] Kings Coll Hosp London, Dept Haematol Med, London, England

[6] Univ Freiburg, Fac Biol, Freiburg, Germany

[7] Univ Childrens Hosp Freiburg, Pediat Hematol & Oncol, Freiburg, Germany

[8] Univ South Australia, Ctr Canc Biol, SA Pathol, Adelaide, SA, Australia

[9] Queen Mary Univ London, Ctr Genom & Child Hlth, Blizard Inst, London, England

[10] Barts Hlth NHS Trust, Dept Haematooncol, St Bartholomews Hosp, London, England

来源：

LEUKEMIA | 2018年 / 32卷 / 11期

关键词：

FAMILIAL MYELODYSPLASTIC SYNDROME; MUTATIONS; ASXL1;

D O I：

10.1038/s41375-018-0134-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：2502 / 2507

页数：6

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