Inpatient and outpatient loop electrosurgery excision procedure for cervical intraepithelial neoplasia: a retrospective analysis

被引:12
作者
Leimbacher, B. [1 ]
Samartzis, N. [1 ]
Imesch, P. [1 ]
Dedes, K. J. [1 ]
Fink, D. [1 ]
Canonica, C. [1 ]
机构
[1] Univ Zurich Hosp, Dept Gynecol, CH-8091 Zurich, Switzerland
关键词
LEEP; Conization; Cervical intraepithelial neoplasia; COLD-KNIFE CONIZATION; WOMEN; TRANSPLANTATION; DIATHERMY; LASER; LEEP;
D O I
10.1007/s00404-011-2148-7
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
To determine whether the outpatient loop electrosurgical excision procedure (LEEP) conization (out-LEEP) is as effective and safe as inpatient LEEP conization (in-LEEP) with regard to the complete removal of cervical dysplasia, recurrence-free survival and post-operative morbidity. 233 patients were included in this retrospective cohort study from January 2002 to December 2007. 181 had outpatient treatment and 52 inpatient treatment. We used Mann-Whitney U test, two-sided Fisher's exact test, Chi-square test, log rank test and Kaplan-Meier curve. Incomplete excision was found in 16/52 (30.8%) cases in the inpatient group and 46/181 (25.4%) in the outpatient group (P = 0.48). Six patients had post-operative complications: two cases of secondary haemorrhage in each group (in-LEEP 3.8%, out-LEEP 1.1%, P = 0.22) and two cases of cervical stenosis amongst inpatients (3.8%, P = 0.049). Alteration of specimen by thermal artifact were reported in 4/52 (7.7%) of in-LEEP cones and 10/181 (5.5%) of out-LEEP cones (P = 0.52). Measurements of cones in both groups were comparable with a mean depth of 9.35 mm (+/- 5.5 mm) and 8.4 mm (+/- 3.4 mm), respectively. Our results suggest that efficacy and safety of ambulatory LEEP conization is comparable as in inpatient procedure.
引用
收藏
页码:1441 / 1445
页数:5
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