Bioengineered Scaffolds for Stem Cell Applications in Tissue Engineering and Regenerative Medicine

被引：27

作者：

Rahmati, Maryam ^{[1
,2
,3
]}

Pennisi, Cristian Pablo ^{[4
]}

Mobasheri, Ali ^{[5
,6
,7
,8
,9
]}

Mozafari, Masoud ^{[1
,2
,3
]}

机构：

[1] Iran Univ Med Sci IUMS, Cellular & Mol Res Ctr, Tehran, Iran

[2] Iran Univ Med Sci IUMS, Fac Adv Technol Med, Dept Tissue Engn & Regenerat Med, Tehran, Iran

[3] Mat & Energy Res Ctr MERC, Nanotechnol & Adv Mat Dept, Bioengn Res Grp, Tehran, Iran

[4] Aalborg Univ, Dept Hlth Sci & Technol, Lab Stem Cell Res, Aalborg, Denmark

[5] D BOARD FP7 Consortium, Guildford, Surrey, England

[6] APPROACH IMI Consortium, Guildford, Surrey, England

[7] Univ Surrey, Fac Hlth & Med Sci, Guildford, Surrey, England

[8] Queens Med Ctr, Arthrit Res UK Ctr Sport Exercise & Osteoarthrit, Nottingham, England

[9] State Res Inst Ctr Innovat Med, Dept Regenerat Med, Vilnius, Lithuania

来源：

CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 3: STEM CELLS, BIO-MATERIALS AND TISSUE ENGINEERING | 2018年 / 1107卷

关键词：

Biomaterials; Regenerative medicine; Tissue engineering; Stem cells; Microenvironment; PROTEIN ADSORPTION; BIOACTIVE GLASSES; QUANTUM DOTS; SELF-RENEWAL; HYDROGELS; DIFFERENTIATION; CHITOSAN; DELIVERY; NICHE; POLYSACCHARIDE;

D O I：

10.1007/5584_2018_215

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Stem cell-based therapies, harnessing the ability of stem cells to regenerate damaged or diseased tissues, are under wide-ranging consideration for regenerative medicine applications. However, limitations concerning poor cell persistence and engraftment upon cell transplantation still remain. During the recent years, several types of biomaterials have been investigated to control the fate of the transplanted stem cells, aiming to increase their therapeutic efficiency. In the present chapter we focus on the general properties of some of these biomaterials, which include polymers, ceramics, and nano-biomaterials. In the first part of the chapter, a brief explanation about stem cell biology, sources, and their microenvironment is provided. The second part of the chapter presents some of the most recent studies investigating different types of biomaterials and approaches that aim to mimic the stem cell microenvironment for a more precise control of the stem cell fate.

引用

页码：73 / 89

页数：17

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