The DNA transposon Minos as a tool for transgenesis and functional genomic analysis in vertebrates and invertebrates

被引：23

作者：

Pavlopoulos, Anastasios ^{[1
]}

Oehler, Stefan ^{[1
]}

Kapetanaki, Maria G. ^{[1
]}

Savakis, Charalambos ^{[1
,2
]}

机构：

[1] Fdn Res & Technol, Inst Mol Biol & Biotechnol, Iraklion 71110, Crete, Greece

[2] Univ Crete, Sch Med, Iraklion 71003, Crete, Greece

来源：

GENOME BIOLOGY | 2007年 / 8卷

关键词：

D O I：

10.1186/gb-2007-8-S1-S2

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Transposons are powerful tools for conducting genetic manipulation and functional studies in organisms that are of scientific, economic, or medical interest. Minos, a member of the Tc1/mariner family of DNA transposons, exhibits a low insertional bias and transposes with high frequency in vertebrates and invertebrates. Its use as a tool for transgenesis and genome analysis of rather different animal species is described.

引用

页数：7

共 58 条

[1]

Arca B, 1997, GENETICS, V145, P267

[2] Distribution of the transposable element Minos in the genus Drosophila [J].

Arcà, B ;

Savakis, C .

GENETICA, 2000, 108 (03) :263-267

[3] An enhancer trap in the ascidian Ciona intestinalis identifies enhancers of its Musashi orthologous gene [J].

Awazu, S ;

Sasaki, A ;

Matsuoka, T ;

Satoh, N ;

Sasakura, Y .

DEVELOPMENTAL BIOLOGY, 2004, 275 (02) :459-472

[4] Ten years of enhancer detection: Lessons from the fly [J].

Bellen, HJ .

PLANT CELL, 1999, 11 (12) :2271-2281

[5] The BDGP gene disruption project: Single transposon insertions associated with 40% of Drosophila genes [J].

Bellen, HJ ;

Levis, RW ;

Liao, GC ;

He, YC ;

Carlson, JW ;

Tsang, G ;

Evans-Holm, M ;

Hiesinger, PR ;

Schulze, KL ;

Rubin, GM ;

Hoskins, RA ;

Spradling, AC .

GENETICS, 2004, 167 (02) :761-781

[6] Genetic techniques - A universal marker for transgenic insects [J].

Berghammer, AJ ;

Klingler, M ;

Wimmer, EA .

NATURE, 1999, 402 (6760) :370-371

[7] What transposable elements tell us about genome organization and evolution:: the case of Drosophila [J].

Biémont, C ;

Vieira, C .

CYTOGENETIC AND GENOME RESEARCH, 2005, 110 (1-4) :25-34

[8] Transposable elements and genome evolution:: the case of Drosophila simulans [J].

Biémont, C ;

Vieira, C ;

Borie, N ;

Lepetit, D .

GENETICA, 1999, 107 (1-3) :113-120

[9] Stable and heritable gene silencing in the malaria vector Anopheles stephensi -: art. no. e85 [J].

Brown, AE ;

Bugeon, L ;

Crisanti, A ;

Catteruccia, F .

NUCLEIC ACIDS RESEARCH, 2003, 31 (15) :e85

[10] Stable germline transformation of the malaria mosquito Anopheles stephensi [J].

Catteruccia, F ;

Nolan, T ;

Loukeris, TG ;

Blass, C ;

Savakis, C ;

Kafatos, FC ;

Crisanti, A .

NATURE, 2000, 405 (6789) :959-962

← 1 2 3 4 5 6 →