Saffron against Components of Metabolic Syndrome: Current Status and Prospective

被引：32

作者：

Shafiee, Mojtaba ^{[1
]}

Moghaddam, Nazanin Sadat Aghili ^{[1
]}

Nosrati, Mohammad ^{[7
]}

Tousi, Mahsa ^{[1
]}

Avan, Amir ^{[2
,3
]}

Ryzhikov, Mikhail ^{[8
]}

Parizadeh, Mohammad Reza ^{[2
,4
]}

Fiuji, Hamid ^{[9
]}

Rajabian, Majid ^{[9
]}

Bahreyni, Amirhossein ^{[10
,11
]}

Khazaei, Majid ^{[5
]}

Hassanian, Seyed Mahdi ^{[2
,4
,6
]}

机构：

[1] Mashhad Univ Med Sci, Fac Med, Dept Nutr, Mashhad, Iran

[2] Mashhad Univ Med Sci, Metab Syndrome Res Ctr, Mashhad, Iran

[3] Mashhad Univ Med Sci, Fac Med, Dept Modern Sci & Technol, Mashhad, Iran

[4] Mashhad Univ Med Sci, Fac Med, Dept Med Biochem, Mashhad, Iran

[5] Mashhad Univ Med Sci, Fac Med, Dept Med Physiol, Mashhad, Iran

[6] Mashhad Univ Med Sci, Microanat Res Ctr, Mashhad, Iran

[7] Shahid Beheshti Univ Med Sci, Dept Nutr, Fac Med, Tehran 1983969411, Iran

[8] Washington Univ, Sch Med, Div Pulm & Crit Care Med, St Louis, MO 63130 USA

[9] Payame Noor Univ, Dept Biochem, Mashhad 43391735, Iran

[10] Mazandaran Univ Med Sci, Dept Clin Biochem, Mazandaran 48175866, Iran

[11] Mazandaran Univ Med Sci, Fac Med, Immunogenet Res Ctr, Mazandaran 48175866, Iran

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2017年 / 65卷 / 50期

关键词：

saffron; natural food coloring; phytomedicine; metabolic syndrome; CROCUS-SATIVUS SAFFRON; SYSTOLIC BLOOD-PRESSURE; ACTIVE CONSTITUENT; AQUEOUS EXTRACT; LIPID PROFILE; CROCETIN; ANTIOXIDANT; INSULIN; GLUCOSE; RATS;

D O I：

10.1021/acs.jafc.7b03762

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Saffron, the dried stigmas of Crocus sativus L., is mainly used as a food coloring and flavoring agent. This agricultural product is used in traditional medicine for the treatment of several diseases including asthma, liver disease, menstruation disorders) and, of special interest in this review, metabolic syndrome. Saffron and its active components including crocin, crocetin, and safranal are potential therapeutic candidates for attenuating MetS complications including hypertension, hyperglycemia, obesity, and dyslipidemia. This review summarizes the protective role of saffron and its constituents in the pathogenesis of MetS for a better understanding and hence a better management of this disease.

引用

页码：10837 / 10843

页数：7

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