Exploring the association of the Comprehensive Trail Making Test with driving indexes in patients with Parkinson's disease

被引:6
作者
Beratis, Ion N. [1 ]
Andronas, Nikolaos [1 ]
Fragkiadaki, Stella [1 ]
Kontaxopoulou, Dionysia [1 ]
Pavlou, Dimosthenis [2 ]
Papantoniou, Panagiotis [2 ]
Stamelou, Maria [3 ,4 ]
Stefanis, Leonidas [1 ,5 ]
Yannis, George [2 ]
Papageorgiou, Sokratis G. [1 ]
机构
[1] Univ Athens, Attikon Univ Gen Hosp, Dept Neurol 2, 1 Rimini Str, Athens 12462, Greece
[2] Natl Tech Univ Athens, Sch Civil Engn, Dept Transportat Planning & Engn, 9 Heroon Polytechniou Str, Athens 15780, Greece
[3] HYGEIA Hosp, Parkinsons Dis & Movement Disorders Dept, 4 Erythrou Stavrou Str, Athens 15123, Greece
[4] Univ Athens, Dept Neurol 1, Aiginite Hosp, 72 Vas Sofias Str, Athens 11528, Greece
[5] Acad Athens, Biomed Res Fdn, 4 Soranou Ephessiou Str, Athens 11527, Greece
关键词
Comprehensive Trail Making Test; Trail Making Test; Parkinson's disease; Fitness-to-drive; Driving simulator; COGNITIVE FUNCTIONS; PERFORMANCE; DRIVERS; PEOPLE; VALIDITY; DEFICITS; ABILITY; SAFETY; ONSET;
D O I
10.1016/j.trf.2017.10.007
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
The Trail Making test (TMT) has been identified as predictor of driving ability in patients with Parkinson's disease (PD). However, previous research has not explored the effectiveness of an alternative version of the TMT, namely of the Comprehensive Trail Making Test (CTMT; Reynolds, 2002) to show associations with measures related to driving fitness. Main objective of the current work was to evaluate the capacity of the CTMT to detect associations with fitness to drive related measures in patients with PD. Inclusion criteria were the presence of a valid driver's license, regular car driving, a CDR score <= 0.5, and a Hoehn & Yahr score between 1 and 3. Twelve individuals with PD (Age: Mean = 63.75, SD = 10.50) and 12 cognitively intact individuals (Age: Mean = 63.50, SD = 10.43) were introduced in the study. Collection of data included a comprehensive neurological/neuropsychological assessment and a driving simulation experiment. Certain subtests of the CTMT were more strongly associated with a variety of driving indexes in individuals with PD as compared to the original TMT. In addition, according to the stepwise regression models that were applied, the CTMT was recognized as a more effective predictor of driving behavior than the TMT. The pattern of findings that was observed supports the usefulness of CTMT on detecting associations with fitness to drive related-measures in patients with PD. Underlying factors that may explain the effectiveness of the CTMT could be related to the greater variety of set shifting and inhibition processes that this alternative option integrates as compared to the original TMT. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码:535 / 544
页数:10
相关论文
共 46 条
[21]   PARKINSONISM - ONSET PROGRESSION AND MORTALITY [J].
HOEHN, MM ;
YAHR, MD .
NEUROLOGY, 1967, 17 (05) :427-&
[22]   ACCURACY OF CLINICAL-DIAGNOSIS OF IDIOPATHIC PARKINSONS-DISEASE - A CLINICOPATHOLOGICAL STUDY OF 100 CASES [J].
HUGHES, AJ ;
DANIEL, SE ;
KILFORD, L ;
LEES, AJ .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1992, 55 (03) :181-184
[23]   Excessive Daytime Sleepiness in Patients with Parkinson's Disease [J].
Knie, Bettina ;
Mitra, M. Tanya ;
Logishetty, Kartik ;
Chaudhuri, K. Ray .
CNS DRUGS, 2011, 25 (03) :203-212
[24]   Cognitive dysfunction in non-demented Parkinson's disease patients: Controlled and automatic behavior [J].
Koerts, Janneke ;
Leenders, Klaus L. ;
Brouwer, Wiebo H. .
CORTEX, 2009, 45 (08) :922-929
[25]  
Kortte Kathleen Bechtold, 2002, Appl Neuropsychol, V9, P106, DOI 10.1207/S15324826AN0902_5
[26]   VISUAL-SYSTEM ABNORMALITIES IN PATIENTS WITH PARKINSONS-DISEASE [J].
KUPERSMITH, MJ ;
SHAKIN, E ;
SIEGEL, IM ;
LIEBERMAN, A .
ARCHIVES OF NEUROLOGY, 1982, 39 (05) :284-286
[27]  
Lawton M.P., 1988, Instrumental Activities of Daily Living Scale (IADL)
[28]   Predictive validity of driving-simulator assessments following traumatic brain injury: a preliminary study [J].
Lew, HL ;
Poole, JH ;
Lee, EH ;
Jaffe, DL ;
Huang, HC ;
Brodd, E .
BRAIN INJURY, 2005, 19 (03) :177-188
[29]   Driving in Parkinson's disease:: Mobility, accidents, and sudden onset of sleep at the wheel [J].
Meindorfner, C ;
Körner, Y ;
Möller, JC ;
Stiasny-Kolster, K ;
Oertel, GH ;
Krüger, HP .
MOVEMENT DISORDERS, 2005, 20 (07) :832-842
[30]   THE CLINICAL DEMENTIA RATING (CDR) - CURRENT VERSION AND SCORING RULES [J].
MORRIS, JC .
NEUROLOGY, 1993, 43 (11) :2412-2414