A case of congenital syphilis hepatitis treated effectively with hyperbaric oxygenation

Congenital syphilis (CS) is caused by infection of Treponema pallidum and affects multiple organs including the liver. Here, we report a case of CS with florid signs and symptoms at birth. After treatment of penicillin, the infant developed hepatitis presented by increased transaminase and bilirubin. Subsequent treatment with hyperbaric oxygenation (HBO) proved effective. It is important to implement the World Health Organization's (WHO) recommendation that all pregnant women should be screened for syphilis. HBO is a possible potential effective treatment for hepatitis in CS.