Multilayer 3D Chirality and Its Synthetic Assembly

被引：54

作者：

Wu, Guanzhao ^{[1
,2
]}

Liu, Yangxue ^{[2
]}

Yang, Zhen ^{[1
]}

Katakam, Nandakumar ^{[2
]}

Rouh, Hossein ^{[2
]}

Ahmed, Sultan ^{[2
]}

Unruh, Daniel ^{[2
]}

Surowiec, Kazimierz ^{[2
]}

Li, Guigen ^{[1
,2
]}

机构：

[1] Nanjing Univ, Sch Chem & Chem Engn, Inst Chem & BioMed Sci, Nanjing 210093, Peoples R China

[2] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX 79409 USA

来源：

RESEARCH | 2019年 / 2019卷

基金：

中国国家自然科学基金;

关键词：

C-H FUNCTIONALIZATION; ENANTIOSELECTIVE FORMATION; ASYMMETRIC-SYNTHESIS; PEPTIDE-SYNTHESIS; CATALYSIS; IMINES; BONDS; WATER;

D O I：

10.34133/2019/6717104

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

3D chirality of sandwich type of organic molecules has been discovered. The key element of this chirality is characterized by three layers of structures that are arranged nearly in parallel fashion with one on top and one down from the center plane. Individual enantiomers of these molecules have been fully characterized by spectroscopies with their enantiomeric purity measured by chiral HPLC. The absolute configuration was unambiguously assigned by X-ray diffraction analysis. This is the first multilayer 3D chirality reported and is anticipated to lead to a new research area of asymmetric synthesis and catalysis and to have a broad impact on chemical, medicinal, and material sciences in future.

引用

页数：11

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