Calcium Revisited New Insights Into the Molecular Basis of Long-QT Syndrome

被引：21

作者：

Giudicessi, John R. ^{[1
,2
]}

Ackerman, Michael J. ^{[3
,4
,5
]}

机构：

[1] Mayo Clin, Internal Med Residency Program, Dept Med, Windland Smith Rice Sudden Death Genom Lab, Rochester, MN USA

[2] Mayo Clin, Clinician Investigator Program, Dept Med, Windland Smith Rice Sudden Death Genom Lab, Rochester, MN USA

[3] Mayo Clin, Dept Cardiovasc Dis, Windland Smith Rice Sudden Death Genom Lab, Div Pediat Cardiol, Rochester, MN USA

[4] Mayo Clin, Dept Pediat, Windland Smith Rice Sudden Death Genom Lab, Div Pediat Cardiol, Rochester, MN USA

[5] Mayo Clin, Dept Mol Pharmacol & Expt Therapeut, Windland Smith Rice Sudden Death Genom Lab, Rochester, MN USA

来源：

CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY | 2016年 / 9卷 / 07期

关键词：

calcium; human; ion channel; long-QT syndrome; sudden cardiac death; CARDIAC RYANODINE RECEPTOR; CHANNEL BETA-SUBUNIT; TIMOTHY-SYNDROME; CA2+ CHANNELS; VENTRICULAR-ARRHYTHMIAS; ALPHA(1C) SUBUNIT; HYPERTROPHIC CARDIOMYOPATHY; DEPENDENT INACTIVATION; INTERVAL DURATION; ANCHORING PROTEIN;

D O I：

10.1161/CIRCEP.116.002480

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：30

共 119 条

[1] MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia [J].

Abbott, GW ;

Sesti, F ;

Splawski, I ;

Buck, ME ;

Lehmann, WH ;

Timothy, KW ;

Keating, MT ;

Goldstein, SAN .

CELL, 1999, 97 (02) :175-187

[2] Homozygous/Compound Heterozygous Triadin Mutations Associated With Autosomal-Recessive Long-QT Syndrome and Pediatric Sudden Cardiac Arrest Elucidation of the Triadin Knockout Syndrome [J].

Altmann, Helene M. ;

Tester, David J. ;

Will, Melissa L. ;

Middha, Sumit ;

Evans, Jared M. ;

Eckloff, Bruce W. ;

Ackerman, Michael J. .

CIRCULATION, 2015, 131 (23) :2051-2060

[3] Dual role of junctin in the regulation of ryanodine receptors and calcium release in cardiac ventricular myocytes [J].

Altschafl, Beth A. ;

Arvanitis, Demetrios A. ;

Fuentes, Oscar ;

Yuan, Qunying ;

Kranias, Evangelia G. ;

Valdivia, Hector H. .

JOURNAL OF PHYSIOLOGY-LONDON, 2011, 589 (24) :6063-6080

[4]

[Anonymous], 1997, CIRC RES, V81, P526

[5] Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization [J].

Arking, Dan E. ;

Pulit, Sara L. ;

Crotti, Lia ;

Van der Harst, Pim ;

Munroe, Patricia B. ;

Koopmann, Tamara T. ;

Sotoodehnia, Nona ;

Rossin, Elizabeth J. ;

Morley, Michael ;

Wang, Xinchen ;

Johnson, Andrew D. ;

Lundby, Alicia ;

Gudbjartsson, Daniel F. ;

Noseworthy, Peter A. ;

Eijgelsheim, Mark ;

Bradford, Yuki ;

Tarasov, Kirill V. ;

Dorr, Marcus ;

Miiller-Nurasyid, Martina ;

Lahtinen, Annukka M. ;

Nolte, Ilja M. ;

Smith, Albert Vernon ;

Bis, Joshua C. ;

Isaacs, Aaron ;

Newhouse, Stephen J. ;

Evans, Daniel S. ;

Post, Wendy S. ;

Waggott, Daryl ;

Lyytikainen, Leo-Pekka ;

Hicks, Andrew A. ;

Eisele, Lewin ;

Ellinghaus, David ;

Hayward, Caroline ;

Navarro, Pau ;

Ulivi, Sheila ;

Tanaka, Toshiko ;

Tester, David J. ;

Chatel, Stephanie ;

Gustafsson, Stefan ;

Kumari, Meena ;

Morris, Richard W. ;

Naluai, Asa T. ;

Padmanabhan, Sandosh ;

Kluttig, Alexander ;

Strohmer, Bernhard ;

Panayiotou, Andrie G. ;

Torres, Maria ;

Knoflach, Michael ;

Hubacek, Jaroslav A. ;

Slowikowski, Kamil .

NATURE GENETICS, 2014, 46 (08) :826-836

[6] Calmodulin binding and inhibition of cardiac muscle calcium release channel (ryanodine receptor) [J].

Balshaw, DM ;

Xu, L ;

Yamaguchi, N ;

Pasek, DA ;

Meissner, G .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (23) :20144-20153

[7] The Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of CaV1.2 L-type calcium channels [J].

Barrett, Curtis F. ;

Tsien, Richard W. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (06) :2157-2162

[8] Cardiac excitation-contraction coupling [J].

Bers, DM .

NATURE, 2002, 415 (6868) :198-205

[9] Macromolecular complexes regulating cardiac ryanodine receptor function [J].

Bers, DM .

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2004, 37 (02) :417-429

[10] Calcium Channel Mutations in Cardiac Arrhythmia Syndromes [J].

Betzenhauser, Matthew J. ;

Pitt, Geoffrey S. ;

Antzelevitch, Charles .

CURRENT MOLECULAR PHARMACOLOGY, 2015, 8 (02) :133-142

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