The Self-Reported Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) and PainDETECT Questionnaires in COVID-19 Survivors with Post-COVID Pain

被引:10
作者
Fernandez-de-las-Penas, Cesar [1 ,2 ]
Antonio Valera-Calero, Juan [3 ,4 ]
Herrero-Montes, Manuel [5 ,6 ]
del-Valle-Loarte, Pablo [7 ]
Rodriguez-Rosado, Rafael [7 ]
Ferrer-Pargada, Diego [8 ]
Arendt-Nielsen, Lars [2 ,9 ]
Paras-Bravo, Paula [5 ,6 ]
机构
[1] Univ Rey Juan Carlos, Dept Phys Therapy Occupat Therapy Rehabil & Phys, Madrid 28922, Spain
[2] Aalborg Univ, Fac Med, Ctr Neuroplast & Pain CNAP, SMI,Dept Hlth Sci & Technol, DK-9220 Aalborg, Denmark
[3] Univ Camilo Jose Cela, Fac Hlth, Dept Physiotherapy, Villanueva De La Canada 28692, Spain
[4] Camilo Jose Cela Univ, Fac Hlth, Dept Physiotherapy, VALTRADOFI Res Grp, Villanueva De La Canada 28692, Spain
[5] Univ Cantabria, Dept Enfermeria, Santander 39008, Spain
[6] Inst Invest Sanitaria Valdecilla IDIVAL, Grp Invest Enfermeria, Santander 39011, Spain
[7] Hosp Univ Severo Ochoa, Dept Internal Med, Leganes 28911, Spain
[8] Hosp Univ Marques Valdecilla, Serv Neumol, Santander 39008, Spain
[9] Aalborg Univ Hosp, Dept Med Gastroenterol, Mech Sense, DK-9000 Aalborg, Denmark
来源
VIRUSES-BASEL | 2022年 / 14卷 / 07期
关键词
COVID-19; pain; long-COVID; neuropathic; S-LANSS; PainDETECT; CENTRAL SENSITIZATION INVENTORY; VALIDATION; SCALE; PHENOTYPE; VERSION;
D O I
10.3390/v14071486
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
This study aimed to analyze correlations between Self-Report Leeds Assessment of Neuropathic Symptoms (S-LANSS) and PainDETECT with proxies of sensitization, pain-related, or psychological/cognitive variables in coronavirus disease, 2019 (COVID-19) survivors exhibiting post-COVID pain. Demographic, clinical, psychological, cognitive, sensitization-associated symptoms, and health-related quality of life were collected in 146 survivors with post-COVID pain. The PainDETECT and S-LANSS questionnaires were used for assessing neuropathic pain-related symptoms. Patients were assessed with a mean of 18.8 (SD 1.8) months after hospitalization. Both questionnaires were positively associated with pain intensity (p < 0.05), anxiety (PainDETECT p < 0.05; S-LANSS p < 0.01), sensitization-associated symptoms (p < 0.01), catastrophism (p < 0.01), and kinesiophobia (p < 0.01) and negatively associated with quality of life (PainDETECT p < 0.05; S-LANSS p < 0.01). Depressive levels were associated with S-LANSS (p < 0.05) but not with PainDETECT. The stepwise regression analyses revealed that 47.2% of S-LANSS was explained by PainDETECT (44.6%), post-COVID pain symptoms duration (1.7%), and weight (1.1%), whereas 51.2% of PainDETECT was explained by S-LANSS (44.6%), sensitization-associated symptoms (5.4%), and anxiety levels (1.2%). A good convergent association between S-LANSS and PainDETECT was found. Additionally, S-LANSS was associated with symptom duration and weight whereas PainDETECT was associated with sensitization-associated symptoms and anxiety levels, suggesting that the two questionnaires evaluate different aspects of the neuropathic pain spectrum in post-COVID pain patients.
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页数:11
相关论文
共 40 条
[1]   Do "central sensitization" questionnaires reflect measures of nociceptive sensitization or psychological constructs? Protocol for a systematic review [J].
Adams, Greig R. ;
Gandhi, Wiebke ;
Harrison, Richard ;
van Reekum, Carien M. ;
Gilron, Ian ;
Salomons, Tim V. .
PAIN REPORTS, 2021, 6 (04) :E962
[2]   Potential for increased prevalence of neuropathic pain after the COVID-19 pandemic [J].
Attal, Nadine ;
Martinez, Valeria ;
Bouhassira, Didier .
PAIN REPORTS, 2021, 6 (01)
[3]   The number of subjects per variable required in linear regression analyses [J].
Austin, Peter C. ;
Steyerberg, Ewout W. .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 2015, 68 (06) :627-636
[4]   Musculoskeletal symptoms and related factors in postacute COVID-19 patients [J].
Bakilan, Fulya ;
Gokmen, Ismail Gunes ;
Ortanca, Burcu ;
Ucan, Anil ;
Eker Guvenc, Sebnem ;
Sahin Mutlu, Fezan ;
Gokmen, Hatice Merve ;
Ekim, Ayse .
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, 2021, 75 (11)
[5]   The S-LANSS score for identifying pain of predominantly neuropathic origin: Validation for use in clinical and postal research [J].
Bennett, MI ;
Smith, BH ;
Torrance, N ;
Potter, J .
JOURNAL OF PAIN, 2005, 6 (03) :149-158
[6]   Pain Burden in Post-COVID-19 Syndrome following Mild COVID-19 Infection [J].
Bileviciute-Ljungar, Indre ;
Norrefalk, Jan-Rickard ;
Borg, Kristian .
JOURNAL OF CLINICAL MEDICINE, 2022, 11 (03)
[7]   Prevalence of chronic pain with neuropathic characteristics in the general population [J].
Bouhassira, Didier ;
Lanteri-Minet, Michel ;
Attal, Nadine ;
Laurent, Bernard ;
Touboul, Chantal .
PAIN, 2008, 136 (03) :380-387
[8]   Stratification of patients based on the Neuropathic Pain Symptom Inventory: development and validation of a new algorithm [J].
Bouhassira, Didier ;
Branders, Samuel ;
Attal, Nadine ;
Fernandes, Ana Mercia ;
Demolle, Dominique ;
Barbour, Julio ;
de Andrade, Daniel Ciampi ;
Pereira, Alvaro .
PAIN, 2021, 162 (04) :1038-1046
[9]   THE PITTSBURGH SLEEP QUALITY INDEX - A NEW INSTRUMENT FOR PSYCHIATRIC PRACTICE AND RESEARCH [J].
BUYSSE, DJ ;
REYNOLDS, CF ;
MONK, TH ;
BERMAN, SR ;
KUPFER, DJ .
PSYCHIATRY RESEARCH, 1989, 28 (02) :193-213
[10]   Exercise Training in Post-COVID-19 Patients: The Need for a Multifactorial Protocol for a Multifactorial Pathophysiology [J].
Cattadori, Gaia ;
Di Marco, Silvia ;
Baravelli, Massimo ;
Picozzi, Anna ;
Ambrosio, Giuseppe .
JOURNAL OF CLINICAL MEDICINE, 2022, 11 (08)