Complete genome sequence and phylogenetic analysis of avian infectious bronchitis virus isolated in India

被引:0
作者
Shilpa, P. [1 ,2 ]
Kirubaharan, J. John [1 ]
Vidhya, M. [1 ]
Rajasekaran, Ranjani [1 ,3 ]
Rajalakshmi, S. [1 ]
机构
[1] Madras Vet Coll, Chennai 600007, Tamil Nadu, India
[2] Vet Dispensary, Vilayur, Kerala, India
[3] Vet Coll & Res Inst, Theni, Tamil Nadu, India
关键词
Bronchitis; H120; variant; Infectious; Mass; 41; genotype; Mutation; Recombination; S1; gene; Virus variants; MOLECULAR CHARACTERIZATION; EMERGENCE; CORONAVIRUS; PROTEIN; STRAIN;
D O I
暂无
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
Emergence of avian infectious bronchitis virus (IBV) variants with altered tissue tropism and host range has been reported from different parts of the world. Little is known about the different IBV variants existing and emerging in India. To explore the same, an IBV isolate, namely B17 isolated from backyard chicken in Tamil Nadu was used in the present study carried out in 2020 at Madras Veterinary College, Tamil Nadu, India. The complete genome of B17 was sequenced and its phylogenetic relationship with the existing vaccine strain genotypes was analysed. The phylogenetic analysis of both S1 gene and complete genome sequence grouped B17 under Mass 41 genotype comprising of M41, Beaudette, H120 and H120 variant with bootstrap value of 95-100%. Further, genomic analysis of B17 revealed the possibilities of emergence of the same from H120 vaccine strain through mutations at various genes.
引用
收藏
页码:693 / 700
页数:8
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