A population based seroepidemiological survey of Chlamydia pneumoniae infections in schoolchildren

被引：6
作者：
Dal Molin, G
Longo, B
Not, T
Poli, A
Campello, C
机构：
[1] Univ Trieste, UCO Igiene & Med Prevent, Dept Publ Med Sci, I-34127 Trieste, Italy
[2] IRCCS Burlo Garofolo, Trieste, Italy
[3] Univ Trieste, UCO Paediat Clin, Dept Reprod & Dev Sci, I-34127 Trieste, Italy
[4] Univ Verona, Dept Med & Publ Hlth, I-37100 Verona, Italy
来源：
JOURNAL OF CLINICAL PATHOLOGY | 2005年 / 58卷 / 06期
关键词：
D O I：
10.1136/jcp.2004.024380
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Aim: A serosurvey was carried out in schoolchildren from a northeastern area of Italy to define the burden of Chlamydia pneumoniae infection. Methods: A sample of 649 schoolchildren underwent a simplified version of the International Study of Asthma and Allergies in Childhood questionnaire and IgG and IgA antibodies were investigated using an enzyme immunoassay, followed by a microimmunofluorescence assay in reactive sera. Results: Of the children examined, 29% and 19.7% had IgG and IgA antibodies, respectively. The IgG prevalence increased with age. No other sociodemographical variable was related to C pneumoniae infection. An association was established between IgA prevalence and previous otitis media. Conclusions: A mesoendemic ( intermediate between high and low endemic level) pattern of C pneumoniae infection is present in schoolchildren from this area and the prevalence rate is related to age. Moreover, this is the first epidemiological evidence of the role of C pneumoniae in otitis.
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收藏
页码：617 / 620
页数：4
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