A Unique Description of Stage IV Extranodal Marginal Zone Lymphoma (EMZL) in an Adolescent Associated With Gamma Heavy Chain Disease

被引：2

作者：

Mittal, Nupur ^{[1
,2
,3
]}

Zhu, Bing ^{[4
]}

Gaitonde, Sujata ^{[4
]}

Lu, Yang ^{[5
]}

Schmidt, Mary Lou ^{[1
]}

机构：

[1] Univ Illinois, Dept Pediat, Div Pediat Hematol Oncol, Chicago, IL 60612 USA

[2] Rush Univ, Med Ctr, Div Pediat Hematol Oncol, Dept Pediat, Chicago, IL 60612 USA

[3] John H Stroger Hosp, Div Pediat Hematol Oncol, Dept Pediat, Chicago, IL USA

[4] Univ Illinois, Dept Pathol, Chicago, IL 60612 USA

[5] Univ Illinois, Dept Radiol, Chicago, IL 60612 USA

来源：

PEDIATRIC BLOOD & CANCER | 2015年 / 62卷 / 05期

关键词：

bendamustine-rituximab; extranodal marginal zone lymphoma; gamma heavy chain disease; pediatric NHL; B-CELL LYMPHOMA; OF-THE-LITERATURE; TISSUE LYMPHOMA; MALT LYMPHOMA; CHILD; GIRL;

D O I：

10.1002/pbc.25419

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Extranodal Marginal zone lymphoma (EMZL) is a rare, usually localized disease in children. Advanced stage EMZL in adults is considered incurable, with prolonged remissions after chemotherapy. Gamma heavy chain disease (HCD) is a rare disease of adults associated with lympho-proliferative processes with no comparable reports in children. A case of stage-IV EMZL with HCD in an adolescent is discussed including treatment with Bendamustine plus Rituximab. The patient remains disease free 18 months from diagnosis. This case highlights necessity for careful diagnostic work-up to identify indolent lymphomas in children which may respond to less toxic chemotherapy than used for common pediatric lymphomas. Pediatr Blood Cancer 2015;62:905-908. (c) 2015 Wiley Periodicals, Inc.

引用

页码：905 / 908

页数：4

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