The need for clean air: The way air pollution and climate change affect allergic rhinitis and asthma

被引：310

作者：

Eguiluz-Gracia, Ibon ^{[1
]}

Mathioudakis, Alexander G. ^{[2
,3
]}

Bartel, Sabine ^{[4
,5
]}

Vijverberg, Susanne J. H. ^{[6
]}

Fuertes, Elaine ^{[7
]}

Comberiati, Pasquale ^{[8
,9
]}

Cai, Yutong Samuel ^{[10
,11
]}

Tomazic, Peter Valentin ^{[12
]}

Diamant, Zuzana ^{[13
,14
,15
]}

Vestbo, Jorgen ^{[2
,3
]}

Galan, Carmen ^{[16
]}

Hoffmann, Barbara ^{[17
]}

机构：

[1] Hosp Reg Univ Malaga UMA, IBIMA, Allergy Unit, Malaga, Spain

[2] Univ Manchester, Manchester Acad Hlth Sci Ctr, Sch Biol Sci, Div Infect Immun & Resp Med, Manchester, Lancs, England

[3] Manchester Univ NHS Fdn Trust, Wythenshawe Hosp, North West Lung Ctr, Southmoor Rd, Manchester, Lancs, England

[4] German Res Ctr Lung Res DZL, Leibniz Lung Ctr, Res Ctr Borstel, Early Life Origins Chron Lung Dis, Borstel, Germany

[5] Univ Groningen, GRIAC Res Inst, Univ Med Ctr Groningen, Dept Pathol & Med Biol, Groningen, Netherlands

[6] Univ Amsterdam, Amsterdam UMC, Dept Resp Med, Amsterdam, Netherlands

[7] Imperial Coll London, Natl Heart & Lung Inst, London, England

[8] Univ Pisa, Dept Clin & Expt Med, Sect Paediat, Pisa, Italy

[9] Sechenov Univ, Dept Clin Immunol & Allergol, Moscow, Russia

[10] Imperial Coll London, Sch Publ Hlth, MRC Ctr Environm & Hlth, Dept Epidemiol & Biostat, London, England

[11] Univ Oxford, George Inst Global Hlth, Oxford, England

[12] Med Univ Graz, Dept Gen ORL Head & Neck Surg, Graz, Austria

[13] Lund Univ, Skane Univ Hosp, Inst Clin Sci, Dept Resp Med & Allergol, Lund, Sweden

[14] Charles Univ Prague, Fac Med 1, Dept Resp Med, Prague, Czech Republic

[15] Thomayer Hosp, Prague, Czech Republic

[16] Univ Cordoba, Int Campus Excellence Agrifood CeiA3, Dept Bot Ecol & Plant Physiol, Cordoba, Spain

[17] Univ Dusseldorf, Med Fac, Inst Occupat Social & Environm Med, Dusseldorf, Germany

来源：

ALLERGY | 2020年 / 75卷 / 09期

基金：

英国医学研究理事会;

关键词：

allergic rhinitis; asthma; climate change; environment; pollution; RESPIRATORY HEALTH; PARTICULATE MATTER; CHILDHOOD ASTHMA; PASSIVE SMOKING; POLLEN SEASON; LUNG-FUNCTION; RISK-FACTORS; EXPOSURE; CHILDREN; IMPACT;

D O I：

10.1111/all.14177

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Air pollution and climate change have a significant impact on human health and well-being and contribute to the onset and aggravation of allergic rhinitis and asthma among other chronic respiratory diseases. In Westernized countries, households have experienced a process of increasing insulation and individuals tend to spend most of their time indoors. These sequelae implicate a high exposure to indoor allergens (house dust mites, pets, molds, etc), tobacco smoke, and other pollutants, which have an impact on respiratory health. Outdoor air pollution derived from traffic and other human activities not only has a direct negative effect on human health but also enhances the allergenicity of some plants and contributes to global warming. Climate change modifies the availability and distribution of plant- and fungal-derived allergens and increases the frequency of extreme climate events. This review summarizes the effects of indoor air pollution, outdoor air pollution, and subsequent climate change on asthma and allergic rhinitis in children and adults and addresses the policy adjustments and lifestyle changes required to mitigate their deleterious effects.

引用

页码：2170 / 2184

页数：15

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