Hypothermia for neuroprotection after cardiac arrest: Mechanisms, clinical trials and patient care

被引：59
作者：
Froehler, Michael T.
Geocadin, Romergryko G.
机构：
[1] Johns Hopkins Univ Hosp, Dept Neurol, Baltimore, MD 21287 USA
[2] Johns Hopkins Univ Hosp, Dept Neurosurg & Anesthesiol Crit Care Med, Baltimore, MD 21287 USA
来源：
JOURNAL OF THE NEUROLOGICAL SCIENCES | 2007年 / 261卷 / 1-2期
关键词：
cardiovascular disease; cardiac arrest; cerebral perfusion; hypothermia; prognosis; coma;
D O I：
10.1016/j.jns.2007.04.042
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Therapeutic hypothermia is a proven part of cardio-cerebral resuscitation after cardiac arrest as it improves neurologic outcomes after hypoxic brain injury. This article reviews the mechanisms of hypothermic neuroprotection, the clinical trials that support its use after cardiac arrest, as well as the impact of hypothermia on patient management and prognosis. In caring for patients suffering hypoxic brain injury after cardiac arrest, the role of the neurologist is no longer limited to prognosis but is now to become actively involved in clinical management which includes the use of therapeutic hypothermia. (C) 2007 Published by Elsevier B.V.
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收藏
页码：118 / 126
页数：9
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