Currently available Antiepileptic drugs

被引:26
作者
Schachter, Steven C. [1 ]
机构
[1] Harvard Med Sch, Boston, MA 02215 USA
关键词
epilepsy; seizure; antiepileptic drug; refractory; side effects; NEURAL-TUBE DEFECTS; CONGENITAL-MALFORMATIONS; PARTIAL EPILEPSY; VALPROATE; LAMOTRIGINE; PHARMACOKINETICS; TOPIRAMATE; SAFETY; ZONISAMIDE; WOMEN;
D O I
10.1016/j.nurt.2006.11.005
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Many new antiepileptic drugs ( AEDs) have become available over the past 15 years. At the same time, the emphasis on treating patients with epilepsy has grown from stopping seizures to avoiding side effects and maximizing quality of life. This review summarizes currently available AEDs, and presents general treatment principles and guidelines for AED selection. Unfortunately, despite the increased treatment options of today, seizure freedom without side effects remains unattainable for too many patients with epilepsy. Consequently, there remains a significant need for further development of new therapies.
引用
收藏
页码:4 / 11
页数:8
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