RETRACTED: Facile synthesis of porous MoS2 nanofibers for efficient drug delivery and cancer treatment (Retracted Article)

被引：2
|
作者：
Liu, Shaobo [1 ]
Wang, Yan [2 ]
机构：
[1] Gen Hosp Pangang Grp, Operat Dept, Panzhihua 617000, Sichuan, Peoples R China
[2] Henan Univ, Basic Med, Zhengzhou 450000, Henan, Peoples R China
来源：
NANOTECHNOLOGY | 2021年 / 32卷 / 38期
关键词：
porous MoS2 nanofiber; pH and NIR responsive; doxorubicin; drug delivery; cancer therapy; ISOCARBOPHOS DEGRADING BACTERIUM; DEGRADATION; RELEASE; NANOCARRIERS; CHEMOTHERAPY; NANOSHEETS; THERAPY; METHYL; METAL; DOTS;
D O I：
10.1088/1361-6528/ac0a18
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Porous MoS2 nanofibers were synthesized by electroplating and post-annealing and applied in a responsive drug delivery system. The one-dimensional (1D) MoS2 nanofibers displayed a high specific surface area, controllable morphology, and uniform size, serving as a promising drug carrier for chemotherapy. After surface modification with polyethylene glycol (PEG) through PEGylation, the MoS2/PEG composite displayed excellent physical/chemical stability and biocompatibility. More importantly, MoS2/PEG loaded with doxorubicin (DOX) exhibited a controllable release responsive to pH and near-infrared (NIR) irradiation and demonstrated precise DOX dose release. Such remarkable anticancer effects were mainly attributed to outstanding photothermal performance and stability of porous MoS2 nanofibers. This work offered a new opportunity of employing porous MoS2 nanofibers as drug carriers for effective cancer chemotherapy.
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页数：9
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