Solid-phase synthesis of natural product-like macrocycles by a sequence of Ugi-4CR and SNAr-based cycloetherification

被引：58

作者：

Cristau, P

Vors, JP

Zhu, JP ^{[1
]}

机构：

[1] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France

[2] Bayer Cropsci, F-69009 Lyon, France

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 30期

关键词：

D O I：

10.1016/S0040-4039(03)01378-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An on-resin Ugi four-component reaction followed by an intramolecular nucleophilic aromatic substitution (SNAr) has been developed for the rapid access to biaryl-ether containing macrocycles. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：5575 / 5578

页数：4

共 46 条

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