Performance properties of filter paper devices for whole blood collection

被引：41

作者：

Mei, Joanne V. ^{[1
]}

Zobel, Sherri D. ^{[1
]}

Hall, Elizabeth M. ^{[1
]}

De Jesus, Victor R. ^{[1
]}

Adam, Barbara W. ^{[1
]}

Hannon, W. Harry ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Chamblee, GA 30341 USA

来源：

BIOANALYSIS | 2010年 / 2卷 / 08期

关键词：

HIV-INFECTION; SPOT SAMPLES; PHENYLALANINE;

D O I：

10.4155/BIO.10.73

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Background: The Newborn Screening Quality Assurance Program at the Centers for Disease Control and Prevention assesses the adherence to established performance standards of manufactured lots of whole blood filter paper collection devices that are registered by the US FDA. We examined 26 newborn screening analytes measured from blood applied to filter papers from two FDA-cleared sources, Whatman (R) Grade 903 and Ahlstrom Grade 226. The dried blood spots contained analytes at both single levels and dose response series. Results: We observed overlap at one standard deviation for each analyte, with no more than 4-5% difference between the papers. Conclusion: The data demonstrated similarities of analyte recovery between the papers, indicating comparability of the devices for newborn screening and other applications.

引用

页码：1397 / 1403

页数：7

共 16 条

[1]

Adam BW, 2000, CLIN CHEM, V46, P126

[2]

Centers for Disease Control and Prevention (CDC), LAB QUAL ASS STAND P

[3] Assessment of DNA contamination from dried blood spots and determination of DNA yield and function using archival newborn dried blood spots [J].