Presence of formaldehyde in topical corticosteroid preparations available on the Swedish market

被引：8

作者：

Goon, ATJ ^{[1
]}

Gruvberger, B ^{[1
]}

Persson, L ^{[1
]}

Isaksson, M ^{[1
]}

Bruze, M ^{[1
]}

机构：

[1] Natl Skin Ctr, Singapore 308205, Singapore

来源：

CONTACT DERMATITIS | 2003年 / 48卷 / 04期

关键词：

chromotropic acid; corticosteroids; formaldehyde; high-performance liquid chromatography; isopropanol;

D O I：

10.1034/j.1600-0536.2003.00082.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The aim of this study was to investigate the formaldehyde content of topical corticosteroid preparations available on the Swedish market. 73 samples were analysed with the chromotropic acid (CA) method for semi-quantitative formaldehyde determination and 30 samples with a high-performance liquid chromatographic method. These included 24 ointments, 28 creams, 1 lotion, 6 liniments, 2 gels, 9 solutions, 2 mousses and 1 oral paste. Formaldehyde was found in 5 creams and 1 ointment. Sources of formaldehyde in these preparations were discussed. Isopropanol was identified as a probable source of yellow discoloration, leading to false-negative results with the CA method.

引用

页码：199 / 203

页数：5

共 2 条

[1] Quantification of L-carvone in toothpastes available on the Swedish market
Kroona, Liv
Warfvinge, Gunnar
Isaksson, Marlene
Ahlgren, Camilla
Dahlin, Jakob
Sorensen, Osten
Bruze, Magnus
CONTACT DERMATITIS, 2017, 77 (04) : 224 - 230
[2] Survey of the migration of melamine and formaldehyde from melamine food contact articles available on the UK market
Bradley, EL
Boughtflower, V
Smith, TL
Speck, DR
Castle, L
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 2005, 22 (06): : 597 - 606

← 1 →