Monolateral dual kidney transplantation from marginal donors

被引:15
作者
Veroux, M. [1 ]
Corona, D. [1 ]
Gagliano, M. [1 ]
Macarone, M. [1 ]
Sorbello, M. [1 ]
Giuffrida, G. [1 ]
Cutuli, M. [1 ]
Morello, G. [1 ]
Vizcarra, D. [1 ]
Paratore, A. [1 ]
Veroux, P. [1 ]
机构
[1] Univ Hosp, Dept Surg Sci Transplantat & Adv Technol, Organ Transplant Unit, I-95123 Catania, Italy
关键词
D O I
10.1016/j.transproceed.2007.05.042
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background. Dual kidney transplantation (DKT) offers a safe way to face the organ shortage with good short-term and medium-term renal function. However, its application is limited by the longer operating time and the risk of surgical complication. This study reviews our results with DKT performed with an ipsilateral technique in terms of graft loss, graft and patient survival rates, and surgical complications. Patients and Methods. From January 2002 to March 2006, 23 patients underwent DKT through a monolateral Gibson incision with placement of both kidneys. Results. One primary nonfunction occurred (4%). Delayed graft function was observed in 3 DKT (13.3%). Acute rejection rate was 4.3% (1 patient). All patients are alive at a mean follow-up of 28 months. One-year and 2-year graft survival rates were 100% and 96%, respectively. Mean serum creatinine level at 1-year posttransplantation was 1.3 mg/dL (range, 0.8-2.1 mg/dL). One DKG recipient lost 1 graft, retaining the second normal functioning graft due to ureteral necrosis. The mean hospital stay after transplantation was 15 days (range, 12-34 days). Conclusions. Monolateral placement in DKT offers the advantage of a single incision, minimizing the surgical risk. Tailored immunosuppression and careful selection of potential recipients, by excluding those with severe cardiopulmonary pathologies, could significantly improve both patient and graft survival in this group of patients.
引用
收藏
页码:1800 / 1802
页数:3
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