Recent developments in the diagnosis and management of tuberculosis

被引：49

作者：

Sulis, Giorgia ^{[1
]}

Centis, Rosella ^{[2
]}

Sotgiu, Giovanni ^{[3
]}

D'Ambrosio, Lia ^{[2
,4
]}

Pontali, Emanuele ^{[5
]}

Spanevello, Antonio ^{[6
,7
]}

Matteelli, Alberto ^{[1
]}

Zumla, Alimuddin ^{[8
,9
]}

Migliori, Giovanni Battista ^{[2
]}

机构：

[1] Univ Brescia, WHO Collaborating Ctr TB HIV & TB Eliminat, Dept Infect & Trop Dis, Brescia, Italy

[2] IRCCS, Maugeri Inst, WHO Collaborating Ctr TB & Lung Dis, Pavia, Italy

[3] Univ Sassari, Res Med Educ & Profess Dev Unit, Clin Epidemiol & Med Stat Unit, Dept Biomed Sci,AOU Sassari, Sassari, Italy

[4] Publ Hlth Consulting Grp, Lugano, Switzerland

[5] Galliera Hosp, Dept Infect Dis, Genoa, Italy

[6] IRCCS, Maugeri Inst, Pneumol Unit, Tradate, Italy

[7] Univ Insubria, Dept Clin & Expt Med, Varese, Italy

[8] UCL, Div Infect & Immun, London, England

[9] UCL Hosp NHS Fdn Trust, NIHR Biomed Res Ctr, London, England

来源：

NPJ PRIMARY CARE RESPIRATORY MEDICINE | 2016年 / 26卷

关键词：

MULTIDRUG-RESISTANT TUBERCULOSIS; SCALING-UP; DRUGS; DELAMANID; COMPASSIONATE; PERFORMANCE;

D O I：

10.1038/npjpcrm.2016.78

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Tuberculosis (TB) is a major public health issue worldwide, with similar to 9.6 million new incident cases and 1.5 million deaths in 2014. The End-TB Strategy launched by the World Health Organization in the context of the post-2015 agenda aims to markedly abate the scourge of TB towards global elimination, by improving current diagnostic and therapeutic practices, promoting preventative interventions, stimulating government commitment and increased financing, and intensifying research and innovation. The emergence and spread of multidrug-resistant strains is currently among the greatest concerns, which may hinder the achievement of future goals. It is crucial that primary healthcare providers are sufficiently familiar with the basic principles of TB diagnosis and care, to ensure early case detection and prompt referral to specialised centres for treatment initiation and follow-up. Given their special relationship with patients, they are in the best position to promote educational interventions and identify at-risk individuals as well as to improve adherence to treatment.

引用

页数：8

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