Metformin, a miracle remedy beyond diabetes

被引：0
作者：
Foretz, Marc [1 ]
Viollet, Benoit [1 ]
机构：
[1] Univ Paris 05, Inst Cochin, CNRS UMR8104, Dept Metab Diabet & Canc,Inserm U1016, F-75014 Paris, France
来源：
BIOFUTUR | 2012年 / 329期
关键词：
MECHANISM; CANCER; LKB1; AMPK;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：52 / 57
页数：6
相关论文
共 25 条
[1]   Metformin for aging and cancer prevention [J].
Anisimov, Vladimir N. .
AGING-US, 2010, 2 (11) :760-774
[2]  
[Anonymous], MED MAL METAB
[3]  
[Anonymous], MED MAL METAB
[4]  
Bailey C.J., 2007, Metformin-The Gold Standard: A Scientific Handbook
[5]   Metformin reduces systemic methylglyoxal levels in type 2 diabetes [J].
Beisswenger, PJ ;
Howell, SK ;
Touchette, AD ;
Lal, S ;
Szwergold, BS .
DIABETES, 1999, 48 (01) :198-202
[6]   Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I [J].
El-Mir, MY ;
Nogueira, V ;
Fontaine, E ;
Avéret, N ;
Rigoulet, M ;
Leverve, X .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (01) :223-228
[7]   Regulation of energy metabolism by AMPK: a novel therapeutic approach for the treatment of metabolic and cardiovascular diseases [J].
Foretz, M ;
Taleux, N ;
Guigas, B ;
Horman, S ;
Beauloye, C ;
Andreelli, F ;
Bertrand, L ;
Viollet, B .
M S-MEDECINE SCIENCES, 2006, 22 (04) :381-388
[8]   Cancer towards diabetes treatment: the suppressor of tumor LKB1 as a new pharmacological target [J].
Foretz, M ;
Guigas, B ;
Viollet, B .
M S-MEDECINE SCIENCES, 2006, 22 (04) :348-350
[9]   Regulation of hepatic metabolism by AMPK [J].
Foretz, Marc ;
Viollet, Benoit .
JOURNAL OF HEPATOLOGY, 2011, 54 (04) :827-829
[10]   Mechanism of inhibition of hepatic glucose production by metformin: a new concept for an old remedy [J].
Foretz, Marc ;
Viollet, Benoit .
M S-MEDECINE SCIENCES, 2010, 26 (6-7) :663-666
123