FATAL PARVOVIRUS B19 MYOCARDITIS IN CHILDREN AND POSSIBLE DYSIMMUNE MECHANISM

被引:17
作者
Koehl, Berengere [1 ]
Oualha, Mehdi
Lesage, Fabrice
Rambaud, Caroline [2 ]
Canioni, Danielle [3 ]
Hubert, Philippe [4 ]
Leruez-Ville, Marianne [4 ,5 ]
机构
[1] Hop Necker Enfants Malad, Serv Reanimat Pediat, F-75743 Paris 15, France
[2] Hop Raymond Poincare, Serv Anatomopathol, Garches, France
[3] Hop Necker Enfants Malad, Serv Anatomopathol, F-75743 Paris 15, France
[4] Univ Paris 05, Paris, France
[5] Hop Necker Enfants Malad, Microbiol Serv, Unite Virol, F-75743 Paris 15, France
关键词
myocarditis; parvovirus B19; immune response; B19-ASSOCIATED MYOCARDITIS; INFECTION; DNA; FULMINANT; PREVALENCE;
D O I
10.1097/INF.0b013e3182425786
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We report 2 cases of previously healthy children, who developed, after a common parvovirus B19 infection, a sudden inflammatory response, involving predominantly T cell, directed against myocardium and leading to fatal outcome. These cases and several published case reports further our understanding of fulminating parvovirus myocarditis in children.
引用
收藏
页码:418 / 421
页数:5
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