Enantioselective Synthesis of Chromenes via a Palladium-Catalyzed Asymmetric Redox-Relay Heck Reaction

被引：14
|
作者：
Jiang, Ze-Zhen [1 ,2 ]
Gao, Ang [2 ]
Li, Hao [1 ,2 ]
Chen, Di [2 ]
Ding, Chang-Hua [2 ]
Xu, Bin [1 ]
Hou, Xue-Long [2 ]
机构：
[1] Shanghai Univ, Dept Chem, Innovat Drug Res Ctr, Shanghai 200444, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China
来源：
CHEMISTRY-AN ASIAN JOURNAL | 2017年 / 12卷 / 24期
基金：
中国国家自然科学基金;
关键词：
asymmetric catalysis; boronic acids; chromenes; Heck reaction; palladium;
D O I：
10.1002/asia.201701504
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A palladium-catalyzed asymmetric redox-relay Heck reaction of 4H-chromenes and arylboronic acids has been successfully developed. The reaction proceeded in moderate to good yields with good to high enantioselectivities. The resulting product is an advanced intermediate of bio-active compound BW683C.
引用
收藏
页码：3119 / 3122
页数：4
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