Facile, efficient, catalyst-free, ultrasound-assisted one-pot green synthesis of triazole derivatives

被引：14

作者：

Venigalla, Lalu Sai ^{[1
]}

Maddila, Suresh ^{[1
,2
]}

Jonnalagadda, Sreekantha B. ^{[2
]}

机构：

[1] GITAM Univ, Dept Chem, Visakhapatnam, Andhra Pradesh, India

[2] Univ KwaZulu Natal, Sch Chem & Phys, Westville Campus,Chiltern Hills, ZA-4000 Durban, South Africa

来源：

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2020年 / 17卷 / 07期

基金：

新加坡国家研究基金会;

关键词：

Green synthesis; Catalyst-free; Triazoles; Two-component system; Ultrasonication; One-pot reaction; MULTICOMPONENT; DEGRADATION; OZONATION; PESTICIDE;

D O I：

10.1007/s13738-020-01887-1

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel and efficient ultrasonic-assisted one-pot tandem reaction has been developed for synthesis of triazole derivatives with excellent yield (94-98%) in short reaction time (< 6 min) in the absence of catalyst under ethanol solvent condition. All synthesized molecules were well identified and characterized using various spectral techniques including(1)H,C-13, and(15)N nuclear magnetic resonance (NMR) and high-resolution mass spectrometry (HRMS) analyses. This green protocol offers many benefits including environmental friendliness, clean and simple operation, cost-effectiveness, short reaction time, easy work-up, excellent yield, and reduced waste production, making the method "green" and "ecofriendly benign." Graphic abstract

引用

页码：1539 / 1544

页数：6

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