Biodegradable membrane of poly(l-lactide acid-dioxanone-glycolide) and stereocomplex poly(lactide) with enhanced crystallization and biocompatibility

被引：6
作者：
Fan, Tiantang [1 ,2 ]
Qin, Jingwen [3 ]
Meng, Xiao [4 ]
Li, Jiafeng [5 ]
Liu, Qing [3 ]
Wang, Guannan [1 ,2 ]
机构：
[1] Jining Med Univ, Coll Med Engn, Jining, Peoples R China
[2] Jining Med Univ, Key Lab Med Funct Nanomat, Jining, Peoples R China
[3] Tongji Univ, Shanghai East Hosp, Inst Translat Nanomed, Inst Biomed Engn & Nano Sci,Sch Med, Shanghai, Peoples R China
[4] North China Elect Power Univ, Coll Mat Sci & Engn, Beijing, Peoples R China
[5] China Coal Res Inst, Beijing, Peoples R China
来源：
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY | 2022年 / 10卷
关键词：
poly(l-lactide); stereocomplex poly(lactic acid); crystallization; biodegradability; biocompatibility; KINETICS; COPOLYMER; FIBERS; PLLA;
D O I：
10.3389/fbioe.2022.1021218
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The membranes of poly(l-lactide acid-p-dioxanone-glycolide) (PLPG) with stereocomplex poly(lactic acid) (sc-PLA) were prepared by the solution blending way. It was observed that sc-PLA significantly heightened the crystallizing behavior of PLLA segments of the PLPG matrix. The crystallizing behavior displayed that the temperature of crystallization shifted to a higher range than that of PLPG. Moreover, the half-time of crystallization sharply decreased in value as the sc-PLA content increased in value on account of the pre-eminent nucleation ability of sc-PLA. TGA results revealed the thermal stability of the samples with the increase of sc-PLA compared to PLPG. Meanwhile, enzymatic degradation results indicated that the mass loss rate of the membrane decreased with the introduction of sc-PLA, but the overall degradation ability was still greater than that of PLLA. In the meantime, the biological experiment indicated that the membrane possessed low cytotoxicity.
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页数：11
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共 31 条
[1]   Triangular polymer single crystals: Stereocomplexes, twins, and frustrated structures [J].
Cartier, L ;
Okihara, T ;
Lotz, B .
MACROMOLECULES, 1997, 30 (20) :6313-6322
[2]   Effects of L-lactide and D,L-lactide in poly(lactide-co-glycolide)-poly(ethylene glycol)-poly(lactide-co-glycolide) on the bulk states of triblock copolymers, and their thermogellation and biodegradation in water [J].
Chen, Chang ;
Chen, Lin ;
Cao, Luping ;
Shen, Wenjia ;
Yu, Lin ;
Ding, Jiandong .
RSC ADVANCES, 2014, 4 (17) :8789-8798
[3]   A generalizable strategy toward highly tough and heat-resistant stereocomplex-type polylactide/elastomer blends with substantially enhanced melt processability [J].
Deng, Shihao ;
Yao, Ju ;
Bai, Hongwei ;
Xiu, Hao ;
Zhang, Qin ;
Fu, Qiang .
POLYMER, 2021, 224
[4]   Enhancing crystallization behavior for optimized performances of poly(TMC-b-(LLA-ran-GA)) by PDLA/PLLA stereocomplex crystallization [J].
Fan, Tiantang ;
Qin, Jingwen ;
Lin, Shengli ;
Ye, Wuyou ;
Liu, Qing ;
Fan, Zhongyong ;
Wang, Ye .
POLYMERS FOR ADVANCED TECHNOLOGIES, 2020, 31 (08) :1675-1687
[5]   Enhancement of the crystallization and biocompatibility of poly(TMC-b-(LLA-ran-GA)) by poly(lactide) stereocomplex [J].
Fan, Tiantang ;
Qin, Jingwen ;
Lin, Shengli ;
Ye, Wuyou ;
Li, Jiafeng ;
Zhang, Qin ;
Gong, Li ;
Liu, Dongyang ;
Fan, Zhongyong .
CRYSTENGCOMM, 2019, 21 (41) :6269-6280
[6]   Eumelanin Coated PLA Electrospun Micro Fibers as Bioinspired Cradle for SH-SY5Y Neuroblastoma Cells Growth and Maturation [J].
Fasolino, Ines ;
Bonadies, Irene ;
Ambrosio, Luigi ;
Raucci, Maria Grazia ;
Carfagna, Cosimo ;
Caso, Federica Maria ;
Cimino, Francesca ;
Pezzella, Alessandro .
ACS APPLIED MATERIALS & INTERFACES, 2017, 9 (46) :40070-40076
[7]   Tailoring Crystalline Morphology by High-Efficiency Nucleating Fiber: Toward High-Performance Poly(L-lactide) Biocomposites [J].
Gao, Tao ;
Zhang, Zheng-Min ;
Li, Le ;
Bao, Rui-Ying ;
Liu, Zheng-Ying ;
Xie, Bang-Hu ;
Yang, Ming-Bo ;
Yang, Wei .
ACS APPLIED MATERIALS & INTERFACES, 2018, 10 (23) :20044-20054
[8]   Chain-End Modification: A Starting Point for Controlling Polymer Crystal Nucleation [J].
Hall, Kyle Wm ;
Percec, Simona ;
Shinoda, Wataru ;
Klein, Michael L. .
MACROMOLECULES, 2021, 54 (04) :1599-1610
[9]   RGD constructs with physical anchor groups as polymer co-electrospinnable cell adhesives [J].
Hommes-Schattmann, Paul J. ;
Neffe, Axel T. ;
Ahmad, Bilal ;
Williams, Gareth R. ;
M'Bele, Gael ;
Vanneaux, Valerie ;
Menasche, Philippe ;
Kalfa, David ;
Lendlein, Andreas .
POLYMERS FOR ADVANCED TECHNOLOGIES, 2017, 28 (10) :1312-1317
[10]   Stereocomplexation kinetics of enantiomeric poly(L-lactide)/poly(D-lactide) blends seeded by nanocrystalline cellulose [J].
Jiang, Long ;
Lv, Pei ;
Ma, Piming ;
Bai, Huiyu ;
Dong, Weifu ;
Chen, Mingqing .
RSC ADVANCES, 2015, 5 (87) :71115-71119
1234