Preparation and Characterization of Temperature-Responsive Chromatographic Column Containing Poly(N-isopropylacrylamide) and Poly([2-(methacryloyloxy)ethyl]trimetylammonium chloride)

被引：15

作者：

Dai, Rongji ^{[1
]}

Chen, Lei ^{[1
]}

Liu, Zongjian ^{[1
]}

Wang, Haihui ^{[1
]}

Hu, Dingyu ^{[1
,2
]}

Deng, Yulin ^{[1
]}

机构：

[1] Beijing Inst Technol, Sch Life Sci, Beijing 100081, Peoples R China

[2] Chinese Peoples Armed Police Force Acad, Langfang 065000, Hebei, Peoples R China

来源：

JOURNAL OF APPLIED POLYMER SCIENCE | 2011年 / 121卷 / 04期

关键词：

temperature-responsive polymer; separation; poly(N-isopropylacrylamide); chromatography; poly ([2-(methacryloyloxy)ethyl]trimetyl-ammonium chloride); PERFORMANCE LIQUID-CHROMATOGRAPHY; COPOLYMER BRUSH SURFACES; N-ISOPROPYLACRYLAMIDE; MODIFIED SILICA; POLYMER BRUSH; MOBILE-PHASE; BIOMOLECULES; SEPARATION; CREATINE;

D O I：

10.1002/app.33830

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

This article described the preparation of temperature-responsive chromatographic column containing poly(N-isopropylacrylamide) and poly quaternary ammonium salt. Poly (N-isopropylacrylamide) and poly ([2-(methacryloyloxy)ethyl] trimetylammonium chloride) were synthesized and grafted to amino modified silica gel. The temperature responsive polymer grafted silica gel was characterized using Fourier transform infrared spectroscopy, thermoweight loss, and elemental analysis. The temperature responsive chromatographic column was used to analyze lactic acid and creatine phosphate disodium salt by controlling of the column temperature from 10 to 50 degrees C. The mixture of lactic acid and creatine phosphate disodium salt was baseline separated at pH 6.93. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 121: 2233-2238, 2011

引用

页码：2233 / 2238

页数：6

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