Stimuli-Responsive Regulation of Biocatalysis through Metallic Nanoparticle Interaction

被引:12
作者
da Silva, Rafael T. P. [1 ]
de Barros, Heloise Ribeiro [1 ]
Sandrini, Daiana M. Furlan [1 ]
de Torresi, Susana I. Cordoba [1 ]
机构
[1] Univ Sao Paulo, Inst Quim, BR-05508000 Sao Paulo, SP, Brazil
基金
巴西圣保罗研究基金会;
关键词
ALTERNATING MAGNETIC-FIELD; GOLD NANOPARTICLES; ELECTRON-TRANSFER; GLUCOSE-OXIDASE; ENZYME; IMMOBILIZATION; REGENERATION; STABILITY; PROTEIN; SURFACE;
D O I
10.1021/acs.bioconjchem.1c00515
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The remote control of biocatalytic processes in an extracellular medium is an exciting idea to deliver innovative solutions in the biocatalysis field. With this purpose, metallic nanoparticles (NPs) are great candidates, as their inherent thermal, electric, magnetic, and plasmonic properties can readily be manipulated upon external stimuli. Exploring the unique NP properties beyond an anchoring platform for enzymes brings up the opportunity to extend the efficiency of biocatalysts and modulate their activity through triggered events. In this review, we discuss a set of external stimuli, such as light, electricity, magnetism, and temperature, as tools for the regulation of nanobiocatalysis, including the challenges and perspectives regarding their use. In addition, we elaborate on the use of combined stimuli that create a more refined framework in terms of a multiresponsive system. Finally, we envision this review might instigate researchers in this field of study with a set of promising opportunities in the near future.
引用
收藏
页码:53 / 66
页数:14
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