Enol Silyl Ethers via Copper(II)-Catalyzed C-O Bond Formation

被引：29
作者：
Chan, Daniel G. [1 ]
Winternheimer, David J. [1 ]
Merlic, Craig A. [1 ]
机构：
[1] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
来源：
ORGANIC LETTERS | 2011年 / 13卷 / 10期
基金：
美国国家科学基金会;
关键词：
CROSS-COUPLING REACTIONS; CATALYZED SYNTHESIS; ALIPHATIC-ALCOHOLS; CARBONYL-COMPOUNDS; SYNTHETIC METHODS; TERMINAL ALKYNES; NATURAL-PRODUCTS; CUPRIC ACETATE; DIARYL ETHERS; ALKENYLSILANOLS;
D O I：
10.1021/ol2009297
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Copper(II) acetate catalyzes the coupling of pinacol vinylboronates with silanols producing enol silyl ethers. This represents a novel enol silyl ether synthesis via formation of the C-O bond instead of the conventional Si-O bond. This also constitutes the first transition-metal-catalyzed oxidative cross-coupling with silanols.
引用
收藏
页码：2778 / 2781
页数：4
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