Enol Silyl Ethers via Copper(II)-Catalyzed C-O Bond Formation

被引：30

作者：

Chan, Daniel G. ^{[1
]}

Winternheimer, David J. ^{[1
]}

Merlic, Craig A. ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 10期

基金：

美国国家科学基金会;

关键词：

CROSS-COUPLING REACTIONS; CATALYZED SYNTHESIS; ALIPHATIC-ALCOHOLS; CARBONYL-COMPOUNDS; SYNTHETIC METHODS; TERMINAL ALKYNES; NATURAL-PRODUCTS; CUPRIC ACETATE; DIARYL ETHERS; ALKENYLSILANOLS;

D O I：

10.1021/ol2009297

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Copper(II) acetate catalyzes the coupling of pinacol vinylboronates with silanols producing enol silyl ethers. This represents a novel enol silyl ether synthesis via formation of the C-O bond instead of the conventional Si-O bond. This also constitutes the first transition-metal-catalyzed oxidative cross-coupling with silanols.

引用

页码：2778 / 2781

页数：4

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