Palladium-Catalyzed Denitrogenative Arylation of Sulfoximines and Sulfonamides with Arylhydrazines under Mild Conditions

被引：0
作者：
Peng, Ruyi [1 ,2 ]
Zhao, Zijian [1 ,2 ]
Zhao, Yongxin [1 ]
Luo, Zhenghong [1 ]
Lian, Yan [1 ]
机构：
[1] Huaihua Univ, Sch Chem & Mat Sci, 180 Huaidong Rd, Huaihua 418000, Hunan, Peoples R China
[2] Huaihua Univ, Key Lab Res & Utilizat Ethnomed Plant Resources H, Huaihua 418000, Peoples R China
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2021年 / 31卷 / 03期
关键词：
Palladium catalysis; Sulfoximines; Sulfonamide; Arylhydrazines; Denitrogenative arylation; N-ARYLATION; ARYL BROMIDES; ARYLBORONIC ACIDS; REUSABLE CATALYST; COUPLING REACTION; BOND FORMATION; BORONIC ACIDS; LIGAND-FREE; EFFICIENT; IODIDES;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A Pd(II)-catalyzed direct arylation of NH-sulfoximines and sulfonamides with arylhydrazines hydrochlorides was herein demonstrated without participation of any organic ligands under mild conditions. The oxidative methodology afforded a smooth routine toward N-aryl sulfoximines and sulfonamides with high efficiency (up to 93% yields) and broad functional groups tolerance (up to 40 examples) through a denitrogenative pathway. The protocol was proposed to take place through the free radical pathway based on the results of control reactions and literature explorations.
引用
收藏
页码：333 / 340
页数：8
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