The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin

被引：286
作者：
Lin, CC [1 ]
Shieh, DE [1 ]
机构：
[1] KAOHSIUNG MED COLL,GRAD INST NAT PROD,KAOHSIUNG 807,TAIWAN
来源：
AMERICAN JOURNAL OF CHINESE MEDICINE | 1996年 / 24卷 / 01期
关键词：
D O I：
10.1142/S0192415X96000050
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
Five extracts (n-hexane, chloroform, ethyl acetate, n-butanol and water) of Scutellaria rivularis Benth. were evaluated for their anti-inflammatory activity against carrageenan-induced paw edema in rats and compared with indomethacin. The result indicated that chloroform extract proved to be the most effective in all of the extracts. Consequently, three major components (baicalin, baicalein and wogonin) of the chloroform extract were further tested for their anti-inflammatory activity using the same model. It was found that baicalin exhibits the greatest inhibition activity against carrageenan-induced rat paw edema.
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页码：31 / 36
页数：6
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