Immunoblot analysis of immune response to cell surface antigens of different Helicobacter pylori strains

被引：0

作者：

Karczewska, E ^{[1
]}

Wyle, F ^{[1
]}

Tarnawski, A ^{[1
]}

机构：

[1] UNIV CALIF IRVINE,VET ADM MED CTR,LONG BEACH,CA

来源：

JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY | 1996年 / 47卷 / 01期

关键词：

H-pylori; immunoblot analysis; antigens;

D O I：

暂无

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Infection with H. pylori has been strongly associated with chronic type B gastritis and peptic ulcer disease, although pathogenic mechanisms of H. pylori infection are still unclear. We examined the structure and antigenicity of water extract of 5 H. pylori strains and immunoblotting with homologous immune rabbit serum. All the tested rabbit sera recognized the protein component between 31-66 kD. The 31-66 kD protein bands are highly specific for H. pylori. Only strain isolated from patients with gastric or duodenal ulcer disease gave visible bands with the major proteins 98, 116 kD.

引用

页码：115 / 120

页数：6