Di-tert-butylsilylene (DTBS) group-directed α-selective galactosylation unaffected by C-2 participating functionalities

被引：171

作者：

Imamura, A

Ando, H

Korogi, S

Tanabe, G

Muraoka, O

Ishida, H

Kiso, M

机构：

[1] Gifu Univ, Dept Appl Bioorgan Chem, Gifu 5011193, Japan

[2] Kinki Univ, Sch Pharmaceut Sci, Higashiosaka, Osaka 5778502, Japan

[3] JST, CREST, Gifu 5011193, Japan

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 35期

基金：

日本学术振兴会; 日本科学技术振兴机构;

关键词：

alpha-galactosylation; neighboring participation; di-tert-butylsilylene group;

D O I：

10.1016/S0040-4039(03)01647-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We have discovered an unusual alpha-galactosylation using phenylthioglycoside of 4,6-O-di-tert-butylsilylene (DTBS)-protected galactose derivatives as a glycosyl donor, which was not hampered by the neighboring participation of C-2 acyl functionality such as NTroc and OBz. The power of the DTBS effect has been exemplified by the coupling reaction with various glycosyl acceptors. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：6725 / 6728

页数：4

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