Electrocardiogram Findings in Patients with Alopecia Areata

被引:1
作者
Peterson, Danielle [1 ]
Wambier, Carlos [2 ]
Dai, Feng [3 ]
Lampert, Rachel [4 ]
Ahmad, Tariq [4 ]
Yale, Katerina L. [5 ]
Mesinkovska, Natasha A. [5 ]
King, Brett [1 ]
机构
[1] Yale Sch Med, Dept Dermatol, New Haven, CT 06510 USA
[2] Brown Univ, Dept Dermatol, Providence, RI 02912 USA
[3] Yale Sch Med, Ctr Analyt Sci, New Haven, CT USA
[4] Yale Sch Med, Sect Cardiovasc Med, Dept Internal Med, New Haven, CT 06510 USA
[5] Univ Calif Irvine, Dept Dermatol, Irvine, CA 92717 USA
关键词
Alopecia areata; Bradycardia; Heart rate; Cardiovascular; Autoimmune; T cell; Electrocardiogram; CARDIAC TROPONIN-I; INFLAMMATION;
D O I
10.1007/s13555-021-00614-9
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Introduction: While autoimmune comorbidities are common in alopecia areata, little is known about comorbid cardiovascular disease. The purpose of this study was to evaluate the incidence of bradyarrhythmia in patients with alopecia areata. Methods: Retrospective review of electrocardiograms of 124 patients with >= 50% scalp hair loss (severe alopecia areata) was conducted and compared to National Health and Nutrition Examination Survey (NHANES) data. Results: The prevalence of bradycardia in females with alopecia areata was 24.3% (95% CI, 14.5-34.1%) and in those age 40 years or older was 40.8% (95% CI, 22.2-53.5%) compared to 19.5% in the NHANES III population. The prevalence of bradycardia in males with alopecia areata was 36.0% (95% CI, 22.7-49.3%) and in those age 40 years or older was 50.0% (95% CI, 21.7-78.3%) compared to 26.9% in the NHANES III population. Conclusion: The potential association between bradycardia and alopecia areata merits further investigation.
引用
收藏
页码:2217 / 2223
页数:7
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