Synthesis, Structural Analysis and Antimicrobial Activities of Novel Water Soluble Ionic Liquids Derived from N-Heterocyclic Carbene Salts

被引:3
|
作者
Kunduracioglu, Ahmet [1 ]
Gube, Ozkan [2 ]
Hames-Kocabas, Elif Esin [2 ]
Eyupoglu, Volkan [3 ]
Sonmez, Fatih [4 ]
机构
[1] Pamukkale Univ, Tavas Vocat Coll, Tavas Denizli, Turkey
[2] Aegean Univ, Fac Engn, Dept Bioengn, Bornova, Turkey
[3] Cankiri Karatekin Univ, Fac Sci, Cankiri, Turkey
[4] Sakarya Univ, Pamukova Vocat Coll, Pamukova Sakarya, Turkey
关键词
ionic liquids; N-heterocyclic carbenes; antimicrobial activity; N-functional substituents; BIOLOGICAL EVALUATION; COMPLEXES; NANOPARTICLES; STABILIZATION; CATALYSIS; BIOFILM; AGENTS;
D O I
10.5562/cca2599
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Six N-heterocyclic Carbene based Ionic Liquids (ILs) have been synthesized by conventional methods. The ILs were spectroscopically characterized by NMR and FT-IR techniques. Their in vitro antimicrobial activities were determined towards gram-positive and gram-negative bacterias and yeast strains using minimum inhibition concentration (MIC) assay. The best inhibition performances were obtained with compound 1 due to its more hydrophilic nature compared with the others. It exhibited 1 mg L-1 MIC value against to the most bacteria while the others showed 4 mg L-1.
引用
收藏
页码:105 / 110
页数:6
相关论文
共 50 条
  • [31] Neutral species from "non-protic" N-heterocyclic ionic liquids
    Holloczki, Oldamur
    Nyulaszi, Laszlo
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2011, 9 (08) : 2634 - 2640
  • [32] Synthesis and Structural Characterization of the Gold Complexes of 1,2,4-Triazole Derived N-Heterocyclic Carbene Ligands
    Anuj Kumar
    Manoj Kumar Gangwar
    Mobin M. Shaikh
    Prasenjit Ghosh
    Proceedings of the National Academy of Sciences, India Section A: Physical Sciences, 2016, 86 : 605 - 609
  • [33] Synthesis and Antimicrobial Activity of Novel Ag-N-Heterocyclic Carbene Complexes
    Ozdemir, Ilknur
    Ozcan, Emine Ozge
    Gunal, Selami
    Gurbuz, Nevin
    MOLECULES, 2010, 15 (04): : 2499 - 2508
  • [34] Antimicrobial Activities of Highly Bioavailable Organic Salts and Ionic Liquids from Fluoroquinolones
    Santos, Miguel M.
    Alves, Celso
    Silva, Joana
    Florindo, Catarina
    Costa, Alexandra
    Petrovski, Zeljko
    Marrucho, Isabel M.
    Pedrosa, Rui
    Branco, Luis C.
    PHARMACEUTICS, 2020, 12 (08) : 1 - 15
  • [35] Synthesis, characterization, and investigation of antiproliferative activity of novel Ag (I)-N-Heterocyclic Carbene (NHC) compounds
    Cevik-Yildiz, Esranur
    Sahin, Neslihan
    Sahin-Bolukbasi, Serap
    JOURNAL OF MOLECULAR STRUCTURE, 2020, 1199
  • [36] Organochromium(II) and Organonitridochromium(V) N-Heterocyclic Carbene Complexes: Synthesis and Structural Characterization
    Wang, Juanjuan
    Tan, Gengwen
    An, Dongli
    Zhu, Hongping
    Yang, Ying
    ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 2011, 637 (11): : 1597 - 1601
  • [37] Synthesis and structural characterisation of rhodium hydride complexes bearing N-heterocyclic carbene ligands
    Douglas, S
    Lowe, JP
    Mahon, MF
    Warren, JE
    Whittlesey, MK
    JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2005, 690 (23) : 5027 - 5035
  • [38] Synthesis and Characterization of New Chiral Azolinium Salts, Precursors to N-Heterocyclic Carbenes, Derived from L-Proline
    Thomasset, Amelia
    Bouchardy, Lucie
    Bournaud, Chloee
    Guillot, Regis
    Toffano, Martial
    Giang Vo-Thanh
    SYNTHESIS-STUTTGART, 2014, 46 (02): : 242 - 250
  • [39] Water-soluble N-heterocyclic carbene precursors bearing benzimidazole core: synthesis, characterization, in vitro antioxidant and anticancer studies
    Ulu, Oznur Dogan
    Kurucay, Ali
    Ozdemir, Ismail
    MONATSHEFTE FUR CHEMIE, 2023, 154 (3-4): : 429 - 440
  • [40] Synthesis and Anticancer Activities of some Ag(I) Complexes Involving N-Heterocyclic Carbene Ligands
    Mageed, Ahmed Hassoon
    Hadi, Israa Sami
    CHEMISTRYSELECT, 2024, 9 (05):